Depressive symptoms and cognitive change in older Mexican Americans
Depressive symptoms and cognitive change in older Mexican Americans
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DOI：
10.1177/0891988707303604
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发表时间：
2007-09-01
影响因子：
2.6
通讯作者：
Ottenbacher, Kenneth J.
中科院分区：
文献类型：
--
作者：
Raji, Mukaila A.;Reyes-Ortiz, Carlos A.;Ottenbacher, Kenneth J.
To examine the association between presence of clinically relevant depressive symptoms (Center for Epidemiologic Studies Depression Scale [CES-D] score ! 16) and subsequent cognitive function (Mini-Mental State Examination [MMSE]) over a 7-year period in older Mexican Americans, a prospective cohort study was performed. Five southwestern states contributed data to the Hispanic Established Populations for Epidemiologic Studies of the Elderly. Participants included 2812 noninstitutionalized Mexican Americans aged 65 and older followed from 1993-1994 until 2000-2001. Cognitive change was assessed using the MMSE at baseline and at 2, 5, and 7 years of follow-up. Independent variables were sociodemographics, CES-D ! 16, medical conditions (hypertension, diabetes, coronary artery disease, and stroke), and activities of daily living (ADL) status. A general linear mixed model was used to estimate cognitive change. There was a cross-sectional association between CES-D ! 16 and lower MMSE score (estimate = -0.48; standard error [SE] = 0.15; P
