Prodigious Effects of Concentration Intensification on Nanoparticle Synthesis: A High-Quality, Scalable Approach
Prodigious Effects of Concentration Intensification on Nanoparticle Synthesis: A High-Quality, Scalable Approach
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DOI：
10.1021/jacs.5b10006
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发表时间：
2015-12-23
影响因子：
15
通讯作者：
Robinson, Richard D.
中科院分区：
文献类型：
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作者：
Williamson, Curtis B.;Nevers, Douglas R.;Robinson, Richard D.
实现纳米颗粒技术的前景需要更高效、更稳健的合成方法（即工艺强化），以持续生产大量高质量纳米颗粒 (NP)。我们探索了通过加热方法在前体溶解度极限附近的先前未探索的高浓度范围内合成纳米粒子。我们发现，在这种高度浓缩和粘稠的状态下，纳米颗粒合成参数对实验变异性不太敏感，从而提供了稳健、可扩展和尺寸集中的纳米颗粒合成。具体来说，我们合成了相对于当前大规模（0.1-5克产量）和实验室规模（
Realizing the promise of nanoparticle-based technologies demands more efficient, robust synthesis methods (i.e., process intensification) that consistently produce large quantities of high-quality nanoparticles (NPs). We explored NP synthesis via the heat-up method in a regime of previously unexplored high concentrations near the solubility limit of the precursors. We discovered that in this highly concentrated and viscous regime the NP synthesis parameters are less sensitive to experimental variability and thereby provide a robust, scalable, and size-focusing NP synthesis. Specifically, we synthesize high-quality metal sulfide NPs (200 g) relative to the current field of large-scale (0.1-5 g yields) and laboratory-scale (