Membrane properties and contraction of single muscle fibers in the mouse.
Membrane properties and contraction of single muscle fibers in the mouse.
复制标题
小鼠单肌纤维的膜特性和收缩。
DOI：
10.1152/ajplegacy.1972.222.6.1435
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发表时间：
1972
期刊：
影响因子：
--
通讯作者：
H. Atwood
中科院分区：
文献类型：
--
作者：
A. Luff;H. Atwood
LUFF，A. R.，和H. L.阿特伍德。小鼠单根肌纤维的膜特性和收缩。Am. J.Physiol.222（6）：14351440。1971.用敏感的力电传感器记录了小鼠比目鱼肌（SOL）和趾长伸肌（EDL）单纤维的等长收缩。同时测定了动作电位和膜电常数。在电子显微镜下检查了每块肌肉的一些纤维。SOL中所有测量参数的值范围均比EDL中的值范围更广。然而，SOL纤维的平均达到峰值张力的时间显著长于EDL纤维;平均比膜电阻显著较高，膜电容较低。SOL纤维的动作电位与EDL纤维的动作电位振幅大致相同，但持续时间略长。纤维横小管系统和肌浆网较发达。膜电阻和电容的差异可以归因于超微结构特征。虽然收缩速度的差异主要归因于生物化学差异，但上述膜性质可能与不同的动态性质直接相关。
LUFF, A. R., AND H. L. ATWOOD. Membrane properties and contraction of single muscle fibers in the mouse. Am. J. Physiol. 222(6) : 14351440. 197 1 .-Isometric twitch contractions of single fibers in the soleus (SOL) and extensor digitorum longus (EDL) muscles of the mouse were recorded by means of a sensitive mechanoelectric transducer. Propagated action potentials and membrane electrical constants were also measured. Some fibers from each muscle were examined under an electron microscope. All measured parameters showed a wider range of values in the SOL than in the EDL. However, the mean time-to-peak tension for SOL fibers was significantly longer than that for EDL fibers; mean specific membrane resistance was significantly higher and membrane capacitance was lower. The action potentials of SOL fibers were of about the same amplitude as those of EDL fibers, but of slightly greater duration. The transverse tubular system and sarcoplasmic reticulum were more fully developed in EDL fibers. The differences in membrane resistance and capacitance can be attributed to ultrastructural features. Although differences in contraction speed are largely attributable to biochemical differences, it is likely that the membrane properties described above relate directly to the different dynamic properties.