EFFECT OF DIET AND OVARIECTOMY ON ADIPOSE-TISSUE CELLULARITY IN MICE
EFFECT OF DIET AND OVARIECTOMY ON ADIPOSE-TISSUE CELLULARITY IN MICE
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DOI：
10.1051/rnd:19800404
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发表时间：
1980-01-01
期刊：
影响因子：
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通讯作者：
LEMONNIER, D
中科院分区：
文献类型：
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作者：
PALLIER, E;AUBERT, R;LEMONNIER, D
三周龄雌性小鼠被切除卵巢。从 4 周断奶起，它们被喂食对照或高脂肪饮食。 32 周大时，切除卵巢的小鼠比假手术小鼠的体重要重。sbd。无论喂食哪种饮食。去势后140天食物摄入量减少。喂食对照饮食的卵巢切除小鼠显示出 3 个部位的脂肪细胞肥大和肾周组织增生。在喂食富含脂肪的饮食的小鼠中，卵巢切除术只会导致皮下和肾周脂肪组织进一步肥大。
Three wk old female mice were ovariectomized. From weaning at 4 wk they were fed a control or a high fat diet. When 32 wk old, the ovariectomized mice weighed more than the sham-operated ones.sbd.whichever diet they were fed. Food intake decreased 140 days after castration. Ovariectomized mice fed the control diet showed fat cell hypertrophy at 3 sites and hyperplasia of the perirenal tissue. In mice fed the fat-rich diet, ovariectomy only caused further hypertrophy in the subcutaneous and perirenal adipose tissue.