Effect of gender on intra-abdominal fat in teenagers and young adults.
Effect of gender on intra-abdominal fat in teenagers and young adults.
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性别对青少年腹内脂肪的影响。
DOI：
10.1007/s00247-010-1880-7
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发表时间：
2011
影响因子：
2.3
通讯作者：
Gilsanz,Vicente
中科院分区：
文献类型：
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作者：
Chung,SandraA;Dorey,Frederick;Mittelman,Steven;Gilsanz,Vicente
研究背景：成年男性比成年女性积累更多的腹内脂肪（IAF），这一差异与老年人心脏代谢疾病风险的性别差异密切相关。然而，这种性别差异出现的时间是一个有争议的问题。我们研究了性别对IAF沉积在瘦，超重和肥胖的青少年和年轻人的影响。材料和方法我们测量了505名健康的性成熟青少年和年轻人的皮下腹部脂肪（SAF）和IAF（254名男性，251名女性; 15-22岁），使用一个单一的CT扫描在水平的umbilicus. ResultsNo无论身体大小，年轻女性有更大的SAF值比年轻男性。虽然瘦女性的IAF值高于瘦男性（13.7 ± 7.8 vs. 11.2 ± 5.4;P= 0.001），但超重和肥胖女性和男性的IAF值惊人相似（分别为23.4 ± 11.1 vs. 23.1 ± 9.5;P= 0.88和36.5 ± 20.4 vs. 38.8 ± 13.2;P= 0.59）。相比之下，IAF/SAF的比例在男性中大于女性，除了非常肥胖的人。多元回归分析表明，虽然性别是一个强有力的预测SAF在瘦和超重的科目（P的< 0.0001），它没有影响IAF调整后的身高和体重（P= 0.35和0.65，分别）在超重和肥胖subjects.ConclusionOverweight和肥胖的年轻女性有类似的绝对数额的IAF年轻男子。
BackgroundAdult men accumulate greater intra-abdominal fat (IAF) than adult women, a difference closely related to gender differences in cardiometabolic disease risk in the elderly. However, the time when this gender difference appears is a matter of controversy.ObjectiveWe examine the influence of gender on IAF deposition in lean, overweight and obese teenagers and young adults.Materials and methodsWe measured subcutaneous abdominal fat (SAF) and IAF in 505 healthy sexually mature teenagers and young adults (254 males, 251 females; 15–22 years) using a single CT scan at the level of the umbilicus.ResultsRegardless of body size, young females had greater SAF values than young males. Although lean females had higher IAF values than lean males (13.7 ± 7.8 vs. 11.2 ± 5.4;P= 0.001), overweight and obese females and males had strikingly similar IAF values (23.4 ± 11.1 vs. 23.1 ± 9.5;P= 0.88 and 36.5 ± 20.4 vs. 38.8 ± 13.2;P= 0.59, respectively). In contrast, the ratio of IAF/SAF was greater in males than females, except in the very obese. Multiple regression analysis indicated that while gender was a strong predictor of SAF in lean and overweight subjects (P’s < 0.0001), it did not influence IAF after adjusting for height and weight (P= 0.35 and 0.65, respectively) in overweight and obese subjects.ConclusionOverweight and obese young women have similar absolute amounts of IAF as young men.