Evidence that the fate of class II-disparate corneal grafts is determined by the timing of class II expression.
Evidence that the fate of class II-disparate corneal grafts is determined by the timing of class II expression.
复制标题
有证据表明，II 类不同的角膜移植物的命运是由 II 类表达的时间决定的。
DOI：
10.1097/00007890-199102000-00049
复制
发表时间：
1991
期刊：
影响因子：
6.2
通讯作者：
Niederkorn,J
中科院分区：
文献类型：
--
作者：
Ross,J;Callanan,D;Kunz,H;Niederkorn,J
While the immune privilege nature of the eye affords significant protection to corneal grafts, immunologic rejection is the leading cause of graft failure. Class II antigens are normally absent or expressed at very low levels in normal cornea. The role that class II antigens play in causing graft rejection is particularly interesting. Class II molecules are present on many cells of the immune system, and therefore are important in modulating and mediating immune reactions. The absence of class II bearing cells in the cornea leads to the interesting issue of whether or not those antigens can induce immune rejection of a corneal graft.
