minet: A R/Bioconductor package for inferring large transcriptional networks using mutual information.
minet: A R/Bioconductor package for inferring large transcriptional networks using mutual information.
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DOI:
10.1186/1471-2105-9-461
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发表时间:
2008-10-29
影响因子:
3
通讯作者:
Bontempi, Gianluca
中科院分区:
文献类型:
--
作者:
Meyer, Patrick E.;Lafitte, Frederic;Bontempi, Gianluca
This paper presents the R/Bioconductor package minet (version 1.1.6) which provides a set of functions to infer mutual information networks from a dataset. Once fed with a microarray dataset, the package returns a network where nodes denote genes, edges model statistical dependencies between genes and the weight of an edge quantifies the statistical evidence of a specific (e.g transcriptional) gene-to-gene interaction. Four different entropy estimators are made available in the package minet (empirical, Miller-Madow, Schurmann-Grassberger and shrink) as well as four different inference methods, namely relevance networks, ARACNE, CLR and MRNET. Also, the package integrates accuracy assessment tools, like F-scores, PR-curves and ROC-curves in order to compare the inferred network with a reference one. The package minet provides a series of tools for inferring transcriptional networks from microarray data. It is freely available from the Comprehensive R Archive Network (CRAN) as well as from the Bioconductor website.
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影响因子:
12.3
作者:
Gentleman RC;Carey VJ;Bates DM;Bolstad B;Dettling M;Dudoit S;Ellis B;Gautier L;Ge Y;Gentry J;Hornik K;Hothorn T;Huber W;Iacus S;Irizarry R;Leisch F;Li C;Maechler M;Rossini AJ;Sawitzki G;Smith C;Smyth G;Tierney L;Yang JY;Zhang J
通讯作者:
Zhang J
影响因子:
11.7
作者:
Gardner, Timothy S.;Faith, Jeremiah J.
通讯作者:
Faith, Jeremiah J.
DOI:
10.1073/pnas.220392197
发表时间:
2000-10-24
影响因子:
11.1
作者:
Butte, AJ;Tamayo, P;Kohane, IS
通讯作者:
Kohane, IS
影响因子:
3
作者:
Margolin AA;Nemenman I;Basso K;Wiggins C;Stolovitzky G;Dalla Favera R;Califano A
通讯作者:
Califano A
影响因子:
2.9
作者:
Paninski, L
通讯作者:
Paninski, L