Neural expression of mouse Noelin-1/2 and comparison with other vertebrates.
Neural expression of mouse Noelin-1/2 and comparison with other vertebrates.
复制标题
小鼠Noelin-1/2的神经表达以及与其他脊椎动物的比较。
DOI：
10.1016/s0925-4773(02)00308-8
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发表时间：
2002
影响因子：
2.6
通讯作者：
Bronner-Fraser,Marianne
中科院分区：
文献类型：
--
作者：
Moreno,TanyaA;Bronner-Fraser,Marianne
Noelins是蛙类和鸟类分泌的糖蛋白，具有重要的发育功能。在这里，我们提出的表达模式的小鼠同源物的Noelin-1/2在E8-10的发展，并比较这种模式与其他脊椎动物。在神经板和神经嵴以及颅神经节中观察到表达。随后，在脑组织和肢体极化活动区中表达突出。
Noelins are secreted glycoproteins with important developmental functions in frogs and birds. Here, we present the expression pattern of the mouse homolog of Noelin-1/2 at E8–10 of development and compare this pattern to other vertebrates. Expression was observed in the neural plate and neural crest, as well as in the cranial ganglia. Later, expression is prominent in brain tissue and in the zone of polarizing activity in the limb.