Scattering from laterally heterogeneous vesicles. II. The form factor

Scattering from laterally heterogeneous vesicles. II. The form factor
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DOI:
10.1107/s002188980701206x
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发表时间:
2007-06-01
影响因子:
6.1
通讯作者:
Katsaras, John
Katsaras, John
中科院分区:
材料科学3区
文献类型:
--
作者:
Anghel, Vinicius N. P.;Kucerka, Norbert;Katsaras, John

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尽管在细胞和模型膜中形成域或“筏”的兴趣越来越大,但通过散射技术表征此类系统的尝试相对较少。此前[Pencer et al.(2006). J.Appl.Cryst.39,293 - 303],证明了Porod不变量Q可用于检测横向偏析。在这里,从横向异质囊泡散射的一般理论概述和形状因子推导出包含单个圆形或环形域的囊泡。这些形状因子,然后应用到分析的中子散射数据从异质囊泡。这种技术的潜在优势和局限性进行了讨论。
Despite growing interest in the formation of domains or 'rafts' in cell and model membranes, there have been relatively few attempts to characterize such systems via scattering techniques. Previously [Pencer et al. (2006). J. Appl. Cryst. 39, 293 - 303], it was demonstrated that the Porod invariant, Q, could be used to detect lateral segregation. Here, the general theory for scattering from laterally heterogeneous vesicles is outlined and form factors are derived for vesicles containing either single circular or annular domains. These form factors are then applied to the analysis of neutron scattering data from heterogeneous vesicles. Potential advantages and limitations of this technique are also discussed.