Silver-Catalyzed Benzylation and Allylation of Tertiary Alkyl Bromides with Organozinc Reagents
Silver-Catalyzed Benzylation and Allylation of Tertiary Alkyl Bromides with Organozinc Reagents
复制标题
DOI：
10.1002/asia.201000068
复制
发表时间：
2010-01-01
影响因子：
4.1
通讯作者：
Oshima, Koichiro
中科院分区：
文献类型：
--
作者：
Mitamura, Yukihiro;Asada, Yoshihiro;Oshima, Koichiro
银盐催化叔烷基溴与有机锌试剂的苄基化和烯丙基化反应。反应有效地产生季碳中心。在银催化下，用苄基或烯丙基锌试剂处理偕-二溴代烷烃，导致二苄基化或二烯丙基化。本反应的官能团相容性比以前的格氏试剂的反应更广泛。
Silver salts catalyze the benzylation and allylation of tertiary alkyl bromides with organozinc reagents. The reactions create quaternary carbon centers efficiently. Treatment of gem-dibromoalkanes with benzylic or allylic zinc reagents under silver catalysis leads to dibenzylation or diallylation. The functional-group compatibility of the present reactions is wider than that of the previous reactions with Grignard reagents.