DOMESTIC CASES OF HEMORRHAGIC-FEVER WITH RENAL SYNDROME IN THE UNITED-STATES
DOMESTIC CASES OF HEMORRHAGIC-FEVER WITH RENAL SYNDROME IN THE UNITED-STATES
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DOI：
10.1159/000188086
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发表时间：
1994-09-01
期刊：
影响因子：
2.5
通讯作者：
CHILDS, JE
中科院分区：
文献类型：
--
作者：
GLASS, GE;WATSON, AJ;CHILDS, JE
虽然血清学研究已确定汉他病毒感染在美国，急性疾病尚未得到承认。本研究描述了美国3例国内获得性肾综合征出血热（HFRS）病例。感染是由于首尔病毒（巴尔的摩大鼠病毒）的当地毒株。对临床特征的审查表明，这是一种以恶心、呕吐、肾和肝衰竭为特征的轻度疾病，与其他地方描述的鼠传病毒HFRS相似。对2例患者的随访发现了持续性高血压和肾脏疾病，进一步证明了既往汉他病毒感染与高血压肾脏疾病之间的相关性。
Although serologic studies have identified hantaviral infection in the United States, acute disease has not been recognized. This study describes 3 cases of domestically acquired hemorrhagic fever with renal syndrome (HFRS) in the United States. Infection was due to a local strain of Seoul virus (Baltimore rat virus). A review of the clinical features indicated a mild illness characterized by nausea, vomiting, renal and liver failure similar to HFRS described elsewhere for rat-borne viruses. Follow-up of 2 patients identified persitent hypertension and renal disease providing further evidence of an association between past hantaviral infection and hypertensive renal disease.