Genomic Differences by Race Emerge in Colorectal Cancer.

Genomic Differences by Race Emerge in Colorectal Cancer.
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DOI:
10.1158/2159-8290.cd-nb2021-0330
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发表时间:
2021-06-01
期刊:
影响因子:
28.2
通讯作者:
--
中科院分区:
医学1区
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--
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研究人员在2021年美国癌症研究协会虚拟年会的第一周报告说,黑人、白色人和亚洲/太平洋岛民早发性结直肠癌患者的非沉默突变模式与年龄较晚的患者不同。此外,在早发性癌症患者中,黑人患者的肿瘤突变负荷显著高于白色患者。
Black, white, and Asian/Pacific Islander patients with early-onset colorectal cancer have different patterns of nonsilent mutations than those diagnosed at a later age, researchers reported during the first week of the virtual American Association for Cancer Research Annual Meeting 2021. In addition, among those with early-onset cancer, Black patients had a significantly higher tumor mutation burden than white patients.