A paradigm for biological sulfur transfers via persulfide groups:: a persulfide-disulfide-thiol cycle in 4-thiouridine biosynthesis
A paradigm for biological sulfur transfers via persulfide groups:: a persulfide-disulfide-thiol cycle in 4-thiouridine biosynthesis
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DOI：
10.1039/b208626c
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发表时间：
2002-11-21
影响因子：
4.9
通讯作者：
Mueller, EG
中科院分区：
文献类型：
--
作者：
Wright, CM;Palenchar, PM;Mueller, EG
在4-硫脲生成机制中，硫转移的关键特征是，在没有二硫键还原剂的情况下，ThiI酶只能翻转一次，ThiI的Cys-456接受硫转移酶IscS过硫基团转移的硫。
In support of the key features of sulfur transfer in the proposed mechanisms of 4-thiouridine generation, the enzyme ThiI can turn over only once in the absence of reductants of disulfide bonds, and Cys-456 of ThiI receives the sulfur transferred from the persulfide group of the sulfurtransferase IscS.