Physiology and toxicity of fluoride.
Physiology and toxicity of fluoride.
复制标题
DOI：
10.4103/0970-9290.57379
复制
发表时间：
2009-07-01
期刊：
影响因子：
--
通讯作者：
Bhatnagar, Maheep
中科院分区：
文献类型：
--
作者：
Dhar, Vineet;Bhatnagar, Maheep
氟化物被描述为动物正常发育和生长所需的基本元素，对人类非常有用。氟化物在环境中含量很高，而饮用水是人体摄入氟化物的主要来源。它已被证明在推荐剂量下是有益的，同时其在更高水平下的毒性也已得到充分证实。氟化物在身体的硬组织中积累，并且已知在骨骼和牙齿的矿化中起重要作用。在高水平下，它已被称为导致牙齿和骨骼氟中毒。有建议的影响非常高水平的氟对各种身体器官和遗传物质。本文旨在综述氟化物的各个方面及其在人类生活中的重要性。
Fluoride has been described as an essential element needed for normal development and growth of animals and extremely useful for human beings. Fluoride is abundant in the environment and the main source of fluoride to humans is drinking water. It has been proved to be beneficial in recommended doses, and at the same time its toxicity at higher levels has also been well established. Fluoride gets accumulated in hard tissues of the body and has been know to play an important role in mineralization of bone and teeth. At high levels it has been known to cause dental and skeletal fluorosis. There are suggested effects of very high levels of fluoride on various body organs and genetic material. The purpose of this paper is to review the various aspects of fluoride and its importance in human life.