Imaging of gastric acidity scale by integration of pH-conversion model (pH-CM) into 3D-gastro electrical impedance tomography (3D-g-EIT)
Imaging of gastric acidity scale by integration of pH-conversion model (pH-CM) into 3D-gastro electrical impedance tomography (3D-g-EIT)
复制标题
DOI：
10.1016/j.snb.2022.131923
复制
发表时间：
2022-05-04
影响因子：
8.4
通讯作者：
Takei，Masahiro
中科院分区：
文献类型：
--
作者：
Wicaksono，Ridwan;Darma，Panji N.;Takei，Masahiro
通过将pH转换模型（pH-CM）与三维胃电阻抗成像（3D-g-EIT）相结合，在空间平均氢比电导率σ H+的影响下，实现了对胃酸度的成像。pH-CM使用Debye-Hückel-Onsager（DHO）电子方程、摩尔电导率比、ω H+、粘度η状态（k）和相对介电常数ε状态（k），以便将成像的电导率分布σ转换为pH分布pH*。利用所提出的积分，测量空（S1）、液体存储（S2-S4）和固体粉存储（S5）状态的幻影以反映稀释状态。在空胃（S1）的情况下，以99.50%H2O和0.50%HCl（1.4263g/L）、KCl（0.8647g/L）和NaCl（2.8559g/L）组成的溶液为基础配制人工胃液。在液体储存（S2-S4）状态的情况下，在S2、S3和S4中各加入三次200 mL H2 O作为人工胃液的稀释液。在固体膳食储存（S5）状态下，将酸性固体膳食混合到人工胃内容物中。修正常数α和β是基于每个状态的粘度η状态（k）和介电常数ε状态（k）的变化来计算的。模拟研究了五种状态下胃形模型的电导率。在实验中，模拟模型被测量为胃幻影。将pH-CM集成到3D-g-EIT中成功地在模拟和实验中对pH* 进行了成像。结果表明，酸度标度< pH>与σ H+成反比，模拟和实验的平均pH误差分别为15.8%和8.5%。
The gastric acidity scale has been imaged by integration of the pH-conversion model (pH-CM) into 3D-gastro electrical impedance tomography (3D-g-EIT) under the influence of spatial mean hydrogen-specific conductivity σ H+. The pH-CM uses Debye-Hückel-Onsager (DHO) interionic equation, molar conductivity ratio, ω H+, viscosity η state (k) and relative permittivity ε state (k) in order to convert the imaged conductivity distribution σ to the pH distribution pH*. With the proposed integration, phantoms of empty (S 1), liquid storage (S 2-S 4), and solid meal storage (S 5) states are measured to reflect the dilution state. In the case of empty (S 1), the artificial gastric juice is made based on 99.50% of H 2 O and 0.50% solution consisting of HCl (1.4263 g/L), KCl (0.8647 g/L), and NaCl (2.8559 g/L). In the case of the liquid storage (S 2-S 4) state, 200 mL of H 2 O is added three times as a dilution of artificial gastric juice in each S 2, S 3, and S 4. In the solid meal storage (S 5) state, an acid solid meal is blended into the artificial gastric content. The modified constants, α, and β are calculated based on the variation of viscosity η state (k) and permittivity ε state (k) of each state. The conductivity of gastric-shape models in five states is studied in the simulation. In the experiments, the simulated models were measured as gastric phantoms. Integrating pH-CM into 3D-g-EIT successfully images the pH* in the simulations and experiments. As a result, the estimated acidity scale< pH> is inversely proportional to σ H+ with mean pH error evaluation of simulations e ˆ pH (sim) and experiments e ˆ pH (sim) are 15.8% and 8.5%, respectively.