Studies on the role of the host immune response in recovery from Friend virus leukemia. II. Cell-mediated immunity.
Studies on the role of the host immune response in recovery from Friend virus leukemia. II. Cell-mediated immunity.
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DOI：
10.1084/jem.143.1.85
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发表时间：
1976-01-01
期刊：
影响因子：
--
通讯作者：
Wehrly K
中科院分区：
文献类型：
--
作者：
Chesebro B;Wehrly K
Congenic mouse strains differing only at genes within the H-2 complex were found to have virus-specific cytotoxic effector cells in their spleens during or after recovery from Friend leukemia virus-induced splenomegaly. These effector cells were theta-positive T lymphocytes which functioned in vitro without help or inhibition by B lymphocytes or glass-adherent cells. The antigenic specificities recognized by the effector cells were viral-induced cellular antigens apparently different from those identified by serological techniques.
