The morning surge in blood pressure and heart rate is dependent on levels of physical activity after waking
The morning surge in blood pressure and heart rate is dependent on levels of physical activity after waking
复制标题
早晨血压和心率的激增取决于醒来后的体力活动水平
DOI：
10.1097/00004872-200205000-00020
复制
发表时间：
2002
影响因子：
4.9
通讯作者：
M. Murphy
中科院分区：
文献类型：
--
作者：
A. Leary;A. Struthers;P. Donnan;T. MacDonald;M. Murphy
目的明确晨间体力活动水平对晨峰血压和心率的影响程度。设计与方法采用24小时动态血压监测仪对420例患者的血压和体力活动进行同步监测。晨峰定义为清醒前后4小时内平均血压和心率的差值；还计算了从谷峰到峰值的血压峰值。这些值是根据相同两个时期的平均体力活动(对数转换)的差异进行回归的。在多元线性回归中，对协变量进行了调整，包括年龄、性别、临床血压和降压药的使用。结果平均晨峰血压为23/15(±13/10)mm Hg，心率为17(±10)次/min。觉醒后体力活动几何平均增加33(±1.5)个单位。晨峰收缩压、舒张压和心率的大小均与醒前、醒后平均体力活动差呈显著正相关(P<；0.005)。较高的临床血压与较大的晨间体力活动血压激增显著相关(P<；0.0005)。结论晨峰的大小与醒后几小时的体力活动水平显著相关。在解释动态血压监测结果时，应考虑体力活动。
Objective To define the influence of morning physical activity levels on the magnitude of the morning surge in blood pressure and heart rate. Design and methods Blood pressure and physical activity were simultaneously recorded in 420 patients by 24-h monitor and actigraphy. The morning surge was defined as the difference between mean blood pressure and heart rate values in the 4-h periods before and after waking; the trough-to-peak surge in blood pressure was also calculated. These values were regressed on the difference in mean (log transformed) physical activity for the same two periods. The analysis was adjusted for covariates, including age, sex, clinic blood pressure and use of antihypertensive medication, in a multiple linear regression. Results The mean morning surges in blood pressure and heart rate were 23/15(± 13/10) mmHg and 17(± 10) beats/min, respectively. The geometric mean increase in physical activity after waking was 33(± 1.5) units. The magnitudes of the morning surge in systolic blood pressure, diastolic blood pressure and heart rate were all significantly and positively correlated with the difference in mean physical activity before and after waking (P < 0.005). Greater clinic blood pressure was significantly associated with a greater morning surge in blood pressure on physical activity (P < 0.0005). Conclusions The magnitude of the morning surge is significantly associated with the level of physical activity in the hours after waking. Physical activity should be taken into account when the results of ambulatory blood pressure monitoring are interpreted.