Salivaricin P, one of a family of two-component antilisterial bacteriocins produced by intestinal isolates of Lactobacillus salivarius
Salivaricin P, one of a family of two-component antilisterial bacteriocins produced by intestinal isolates of Lactobacillus salivarius
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DOI：
10.1128/aem.00666-06
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发表时间：
2007-06-01
影响因子：
4.4
通讯作者：
Hill, Colin
中科院分区：
文献类型：
--
作者：
Barrett, Eoin;Hayes, Maria;Hill, Colin
唾液乳杆菌 DPC6005 是一种猪肠道分离株，可产生一种双组分细菌素——唾液素 P，与人类益生菌唾液乳杆菌菌株产生的 ABP-118 具有同源性。事实上，分子表征表明，虽然肽 Sln1 和 AIBP-118 α 相同，但它们的伴侣肽（分别为 Sln2 和 ABP-118 β）有两个氨基酸不同。这一观察结果表明，双组分细菌素可能是肠道唾液乳杆菌菌株的共同特征。
Lactobacfflus salivarius DPC6005, a porcine intestinal isolate, produces a two-component bacteriocin, salivaricin P, with homology to ABP-118 produced by a human probiotic L. salivarius strain. Indeed, molecular characterization revealed that while the peptides Sln1 and AIBP-118 alpha are identical, their companion peptides (Sln2 and ABP-118 beta, respectively) differ by two amino acids. This observation suggests that two-component bacteriocins may be a common feature of intestinal L. salivarius strains.