Powering an inorganic nanodevice with a biomolecular motor
Powering an inorganic nanodevice with a biomolecular motor
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DOI：
10.1126/science.290.5496.1555
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发表时间：
2000-11-24
期刊：
影响因子：
56.9
通讯作者：
Montemagno, CD
中科院分区：
文献类型：
--
作者：
Soong, RK;Bachand, GD;Montemagno, CD
生物分子发动机，如F-1-三磷酸腺苷合成酶(F-1-ATPase)和肌球蛋白在大小上相似，它们产生的力与目前可生产的纳米工程结构兼容。我们设计了单独的生物分子马达和纳米级的无机系统，并描述了它们在由生物分子马达驱动的混合纳米机械设备中的集成。该装置由三个部分组成：工程底物、F-1-ATPase生物分子马达和制造的纳米推进器。用2 mM三磷酸腺苷启动纳米螺旋桨的旋转，用叠氮钠抑制。
Biomolecular motors such as F-1-adenosine triphosphate synthase (F-1-ATPase) and myosin are similar in size, and they generate forces compatible with currently producible nanoengineered structures. We have engineered individual biomolecular motors and nanoscale inorganic systems, and we describe their integration in a hybrid nanomechanical device powered by a biomolecular motor. The device consisted of three components: an engineered substrate, an F-1-ATPase biomolecular motor; and fabricated nanopropellers. Rotation of the nanopropeller was initiated with 2 mM adenosine triphosphate and inhibited by sodium azide.