Transscrotal Near Infrared Spectroscopy as a Diagnostic Test for Testis Torsion in Pediatric Acute Scrotum: A Prospective Comparison to Gold Standard Diagnostic Test Study.
Transscrotal Near Infrared Spectroscopy as a Diagnostic Test for Testis Torsion in Pediatric Acute Scrotum: A Prospective Comparison to Gold Standard Diagnostic Test Study.
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DOI：
10.1016/j.juro.2017.03.134
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发表时间：
2017-09
期刊：
影响因子：
--
通讯作者：
Baker LA
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文献类型：
--
作者：
Schlomer BJ;Keays MA;Grimsby GM;Granberg CF;DaJusta DG;Menon VS;Ostrov L;Sheth KR;Hill M;Sanchez EJ;Harrison CB;Jacobs MA;Huang R;Burgu B;Hennes H;Baker LA
A rapid test for testicular torsion in children may obviate the delay for testicular ultrasound. In this study we assessed testicular tissue percent oxygen saturation (%StO2) measured by transscrotal near infrared spectroscopy as a diagnostic test for pediatric testicular torsion. This was a prospective comparison to a gold standard diagnostic test study that evaluated near infrared spectroscopy %StO2 readings to diagnose testicular torsion. The gold standard for torsion diagnosis was standard clinical care. From 2013 to 2015 males with acute scrotum for more than 1 month and who were less than 18 years old were recruited. Near infrared spectroscopy %StO2 readings were obtained for affected and unaffected testes. Near infrared spectroscopy Δ%StO2 was calculated as unaffected minus affected reading. The utility of near infrared spectroscopy Δ%StO2 to diagnose testis torsion was described with ROC curves. Of 154 eligible patients 121 had near infrared spectroscopy readings. Median near infrared spectroscopy Δ%StO2 in the 36 patients with torsion was 2.0 (IQR −4.2 to 9.8) vs −1.7 (IQR −8.7 to 2.0) in the 85 without torsion (p=0.004). AUC for near infrared spectroscopy as a diagnostic test was 0.66 (95% CI 0.55–0.78). Near infrared spectroscopy Δ%StO2 of 20 or greater had a positive predictive value of 100% and a sensitivity of 22.2%. Tanner stage 3-5 cases without scrotal edema or with pain for 12 hours or less had an AUC of 0.91 (95% CI 0.86–1.0) and 0.80 (95% CI 0.62–0.99), respectively. In all children near infrared spectroscopy readings had limited utility in diagnosing torsion. However, in Tanner 3-5 cases without scrotal edema or with pain 12 hours or less, near infrared spectroscopy discriminated well between torsion and nontorsion.
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DOI：
10.1136/bmj.g7635
发表时间：
2015-01-05
期刊：
BMJ (Clinical research ed.)
影响因子：
--
作者：
Hyttel-Sorensen S;Pellicer A;Alderliesten T;Austin T;van Bel F;Benders M;Claris O;Dempsey E;Franz AR;Fumagalli M;Gluud C;Grevstad B;Hagmann C;Lemmers P;van Oeveren W;Pichler G;Plomgaard AM;Riera J;Sanchez L;Winkel P;Wolf M;Greisen G
通讯作者：
Greisen G
影响因子：
3.5
作者：
Hallacoglu, Bertan;Matulewicz, Richard S.;Fantini, Sergio
通讯作者：
Fantini, Sergio
影响因子：
4.4
作者：
Schoenfeld, Elizabeth M.;Capraro, Geoffrey A.;Visintainer, Paul F.
通讯作者：
Visintainer, Paul F.
影响因子：
19.7
作者：
PATRIQUIN, HB;YAZBECK, S;DUBOIS, J
通讯作者：
DUBOIS, J
影响因子：
4.5
作者：
Molokwu, Chidi N.;Somani, Bhaskar K.;Goodman, Chris M.
通讯作者：
Goodman, Chris M.