The similarity structure of distributed neural responses reveals the multiple representations of letters.

The similarity structure of distributed neural responses reveals the multiple representations of letters.
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DOI:
10.1016/j.neuroimage.2013.11.054
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发表时间:
2014-04-01
期刊:
影响因子:
5.7
通讯作者:
Rapp B
Rapp B
中科院分区:
医学1区
文献类型:
--
作者:
Rothlein D;Rapp B

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大多数关于阅读和拼写的认知理论都认为,字母形状、口语字母名称和运动计划的特定模态表征,以及抽象的、非模态的字母表征有助于统一各种特定模态的格式。然而,基本的问题仍然存在关于抽象的字母表示,不同类型的字母表示的神经地形,以及对正字法信息的皮层选择性的程度。我们直接测试定量模型的相似性/不相似性结构的分布式神经表征的字母使用多变量模式分析-表征相似性分析(MVPA-RSA)探照灯的方法来分析BOLD响应记录从单个字母查看。这些分析揭示了左半球腹侧颞区选择性调谐到抽象的字母表示以及基板调谐到特定模态(视觉,语音和运动)表示的信件。在这项研究中应用的方法解决了以前的研究,已经调查了这些问题的各种缺点,因此,我们报告的研究结果有助于促进我们的理解的性质和格式的表征,发生在阅读和拼写中使用的大规模网络的各个子区域内。
Most cognitive theories of reading and spelling posit modality-specific representations of letter shapes, spoken letter names, and motor plans as well as abstract, amodal letter representations that serve to unify the various modality-specific formats. However, fundamental questions remain regarding the very existence of abstract letter representations, the neuro-topography of the different types of letter representations, and the degree of cortical selectivity for orthographic information. We directly test quantitative models of the similarity/dissimilarity structure of distributed neural representations of letters using Multivariate Pattern Analysis-Representational Similarity Analysis (MVPA-RSA) searchlight methods to analyze the BOLD response recorded from single letter viewing. These analyses reveal a left hemisphere ventral temporal region selectively tuned to abstract letter representations as well as substrates tuned to modality-specific (visual, phonological and motoric) representations of letters. The approaches applied in this research address various shortcoming of previous studies that have investigated these questions and, therefore, the findings we report serve to advance our understanding of the nature and format of the representations that occur within the various sub- regions of the large-scale networks used in reading and spelling.
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