Scavenger receptors: diverse activities and promiscuous binding of polyanionic ligands

Scavenger receptors: diverse activities and promiscuous binding of polyanionic ligands
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DOI:
10.1016/s1074-5521(98)90156-9
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发表时间:
1998-08-01
影响因子:
--
通讯作者:
Gordon, S
Gordon, S
中科院分区:
生物1区
文献类型:
--
作者:
Platt, N;Gordon, S

文献摘要

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清道夫受体是一个不同的蛋白质家族,它们有一个共同的特性--与修饰的脂蛋白结合--但它们最近被证明可以识别各种各样的配体。了解受体-配体结合的分子相互作用应该提供深入了解清道夫受体如何有助于重要的生物过程。
Scavenger receptors are a diverse family of proteins that share a common property - the binding of modified lipoprotein - but they have recently been shown to recognise a diverse range of ligands. Understanding the molecular interaction of receptor-ligand binding should provide insight into how scavenger receptors contribute to important biological processes.