A genomic perspective on the relationship between the Aquificales and the ε-Proteobacteria
A genomic perspective on the relationship between the Aquificales and the ε-Proteobacteria
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DOI：
10.1078/0723-2020-00272
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发表时间：
2004-05-01
影响因子：
3.4
通讯作者：
Vandamme, P
中科院分区：
文献类型：
--
作者：
Coenye, T;Vandamme, P
本研究的目的是确定Aquificales在多大程度上与epsilon-Proteobacteria相关。该种群的几个成员的基因组序列以及水蛭的基因组序列是可用的。在这项研究中，我们利用从这些全基因组序列中提取的信息来进一步了解这些生物体之间的关系，包括共享的假定同源蛋白编码基因的比例，二核苷酸相对丰度值以及16S rRNA基因和20个管家基因的序列。我们的分析结果表明，要对水仙目的系统发育位置得出一致的看法并不容易，但我们的数据清楚地表明，风神单胞菌和epsilon-变形菌门之间没有特别密切的关系，因为(i)它们彼此之间没有比其他远亲生物共享更多的基因，（ii）它们在许多大分子中没有显着的序列相似性。此外，有相当多的证据证实水合水藻位于细菌树的根部附近。
The goal of this study was to determine to what extent the Aquificales are related to the epsilon-Proteobacteria. The genome sequence of several members of this group as well as the genome sequence of Aquifex aeolicus are available. In this study we used information extracted from those whole-genome sequences to gain further insights into the relationships between these organisms, including the fraction of shared putative orthologous protein-encoding genes, dinucleotide relative abundance values and the sequences of the 16S rRNA gene and 20 housekeeping genes. The results of our analyses show that it is not straightforward to come to a consistent picture of the phylogenetic position of the order Aquificales but our data clearly show that there is no particularly close relationship between A. aeolicus and the epsilon-Proteobacteria as (i) they do not share more genes with each other than do other distantly related organisms and (ii) they do not share significant sequence similarity in many macromolecules. In addition, there is considerable evidence that confirms the placement of the Aquificales near the root of the bacterial tree.