Report of the Thirteenth International Symposium of the Foundation for Promotion of Cancer Research: cancer screening-past, present and future.
Report of the Thirteenth International Symposium of the Foundation for Promotion of Cancer Research: cancer screening-past, present and future.
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癌症研究促进基金会第十三届国际研讨会报告：癌症筛查——过去、现在和未来。
DOI：
10.1093/jjco/hyd082
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发表时间：
2000
影响因子：
2.4
通讯作者：
T. Sugimura
中科院分区：
文献类型：
--
作者：
P. Davis;M. Hakama;S. Hisamichi;T. Kakizoe;T. Sano;T. Sugimura
Sugimura博士（东京国立癌症中心）致欢迎辞，并回顾了之前的研讨会，这些研讨会关注器官特异性癌症的基础和临床研究以及他个人对癌症筛查的看法（1,2）。自1981年以来，癌症一直是日本的主要死亡原因，在早期发现和治疗方面存在许多问题。多阶段癌变的作用已经被提出，导致从正常组织到癌前病变和早期癌症的进展及其与检测时间的关系(3)。Kakizoe博士（东京国立癌症中心）在开幕词中提出了癌症检测机制的问题。这些包括出现症状或随后进行自检，两者都不确定检测阶段和无症状阶段的表现。正是后者是本次研讨会的简要内容，即促进早期发现，从而早期和最有效的治疗。还包括对癌症发展的未来预测，通过乳腺癌中的brca1和brca2基因等基因研究进行检测，这将允许仔细的随访，化学预防和预防性治疗。会话1
Dr Sugimura (National Cancer Center, Tokyo) opened the symposium with a welcome address and a review of the previous symposia, which have looked at fundamental and clinical research in organ-specific cancer and his personal view of cancer screening (1,2). Since 1981, cancer has been the leading cause of death in Japan and there are many questions relating to early detection and treatment. The role of multistage carcinogenesis has been raised, leading to a progression from normal tissue to precancerous lesions and early cancer with its relationship to the timing of detection (3). Dr Kakizoe (NCC, Tokyo), in the opening address, raised the issues of the mechanisms of cancer detection. These included presentation with symptoms or following self-check examination, both with uncertainty as to the stage of detection and presentation in the asymptomatic stage. It is the latter which was the brief of this symposium, to promote early detection and hence early and most effective treatment. Also included was the future prediction of cancer development, with detection through genetic studies such as the BRCA 1 and 2 genes in breast cancer, which would allow careful follow-up, chemoprevention and prophylactic treatment. SESSION 1