The Use of Rectal Douches among HIV-uninfected and Infected Men who Have Unprotected Receptive Anal Intercourse: Implications for Rectal Microbicides
The Use of Rectal Douches among HIV-uninfected and Infected Men who Have Unprotected Receptive Anal Intercourse: Implications for Rectal Microbicides
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DOI：
10.1007/s10461-007-9301-0
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发表时间：
2008-11-01
影响因子：
4.4
通讯作者：
Remien, Robert H.
中科院分区：
文献类型：
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作者：
Carballo-Dieguez, Alex;Bauermeister, Jose A.;Remien, Robert H.
虽然一些直肠冲洗导致表面上皮细胞损失和潜在的艾滋病毒传播增加，但男男性行为者（MSM）继续使用它们。我们描述了这种做法的患病率在男男性接触者从事无保护的接受性肛交（URAI）在危险的情况下。一个多种族的样本与艾滋病毒阴性的男男性接触者谁有URAI在前一年的代表性过高，完全通过互联网招募。受试者为105名MSM（78名HIV阴性，27名HIV阳性）。总共有53%的艾滋病毒阴性男子和96%的艾滋病毒阳性男子在准备性行为时进行冲洗，其中大多数经常或总是进行冲洗，主要是为了卫生目的。27%的艾滋病毒阴性和44%的艾滋病毒阳性在性行为后冲洗，部分认为冲洗可以防止感染。冲洗的做法开始在25岁左右。回归分析发现，在控制人口统计学特征和URAI次数后，HIV状态和冲洗次数之间的关联仍然存在。直肠灌洗准备性行为是常见的男性谁实践URAI。这一人群可以受益于避孕套的替代品，如直肠杀微生物剂。考虑到性交前冲洗的普及和频率，一种可以释放直肠杀微生物剂的无害直肠冲洗可能具有很大的可接受性。
Although some rectal douches result in surface epithelium loss and potential increase of HIV transmission, men who have sex with men (MSM) continue to use them. We describe the prevalence of this practice among MSM engaging in unprotected receptive anal intercourse (URAI) in risky circumstances. A multiethnic sample with overrepresentation of HIV-negative MSM who had URAI in the previous year was recruited exclusively through the Internet. Participants were 105 MSM (78 HIV-negative, 27 HIV-positive). A total of 53% of HIV-negative and 96% of HIV-positive men douched in preparation for sex, most of them frequently or always, mainly for hygienic purposes. 27% of HIV-negative and 44% of HIV-positive douched after sex, partly believing douching protected from infections. Douching practices started around age 25. Regression analyses found the association between HIV status and douching occasions persisted after controlling for demographic characteristics and number of URAI occasions. Rectal douching in preparation for sex is common among men who practice URAI. This population could benefit from alternatives to condoms, such as rectal microbicides. Given the popularity of pre-coital douching and its frequency, a harmless rectal douche that could deliver a rectal microbicide could have great acceptability.