Detection of fungal development in closed spaces through the determination of specific chemical targets
Detection of fungal development in closed spaces through the determination of specific chemical targets
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DOI：
10.1016/j.chemosphere.2008.01.057
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发表时间：
2008-05-01
期刊：
影响因子：
8.8
通讯作者：
Oturan, Mehmet A.
中科院分区：
文献类型：
--
作者：
Moularat, Stephane;Robine, Enric;Oturan, Mehmet A.
除了建筑物中遇到的生物降解问题之外，居住者接触霉菌还会导致多种疾病：感染（侵袭性医院曲霉菌病）、即时或延迟过敏、食源性感染和不同类型的刺激。在这种背景下，我们工作的目的是确定建筑材料上真菌发育的特定化学示踪剂。更一般地说，通过检测真菌发育的特定化学指纹，我们的目标是提出一种微生物警报系统，该系统可以控制室内区域微生物处理的系统和/或程序。因此，我们对六种受霉菌人为污染的建筑材料的化学排放进行了表征。建立了 19 种专门来自真菌代谢的化合物的化学指纹图谱：2-乙基己酸甲酯、1-辛烯-3-醇、3-庚醇、3-甲基-1-丁醇、2-甲基-1-丁醇、1,3-辛二烯、2-(5H)-呋喃酮、2-庚烯、α-蒎烯、2-甲基异冰片、4-庚酮、 2-甲基呋喃、3-甲基呋喃、二甲基二硫醚、甲氧基苯、一种萜类化合物和三种倍半萜烯。确定这些化合物的来源及其与生长底物或真菌物种的具体联系，可以判断选择这些化合物作为示踪剂的相关性。因此，检测真菌生长第二天排放的特定挥发性有机化合物表明，该方法具有在出现任何明显污染迹象之前可靠、快速检测真菌发育的优点可以被检测到。 (C) 2008 Elsevier Ltd. 保留所有权利。
In addition to the biodegradation problems encountered in buildings, exposure of their occupants to moulds is responsible for numerous diseases: infections (invasive nosocomial aspergillosis), immediate or delayed allergies, food-borne infections and different types of irritation. In this context, the aim of our work has been to determine specific chemical tracers for fungal development on construction materials. More generally, by detecting a specific chemical fingerprint of fungal development, our objective was to propose a microbiological alert system which could control systems and/or procedures for the microbiological treatment of indoor areas.We therefore characterized the chemical emissions from six types of construction material contaminated artificially by moulds. Chemical fingerprints were established for 19 compounds arising specifically from fungal metabolism: 2-ethylhexanoic acid methyl ester, 1-octen-3-ol, 3-heptanol, 3-methyl-1-butanol, 2-methyl-1-butanol, 1,3-octadiene, 2-(5H)-furanone, 2-heptene, alpha-pinene, 2-methylisoborneol, 4-heptanone, 2-methylfuran, 3-methylfuran, dimethyldisulfide, methoxybenzene, a terpenoid and three sesquiterpenes.Determining the origin of these compounds and their specific links with a growth substrate or fungal species made it possible to judge the pertinence of choosing these compounds as tracers.Thus the detecting specific volatile organic compounds emitted as from the second day of fungal growth demonstrated that this approach had the advantage of detecting fungal development both reliably and rapidly before any visible signs of contamination could be detected. (C) 2008 Elsevier Ltd. All rights reserved.