Estimation of premorbid IQ in individuals with Alzheimer's disease using Japanese ideographic script (Kanji) compound words:: Japanese version of National Adult Reading Test
Estimation of premorbid IQ in individuals with Alzheimer's disease using Japanese ideographic script (Kanji) compound words:: Japanese version of National Adult Reading Test
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DOI：
10.1111/j.1440-1819.2006.01510.x
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发表时间：
2006-06-01
影响因子：
11.9
通讯作者：
Kim, Yoshiharu
中科院分区：
文献类型：
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作者：
Matsuoka, Keiko;Uno, Masatake;Kim, Yoshiharu
国家成人阅读测试（NART）被广泛用于测量英语痴呆患者的发病前智商。本研究的目的是利用50个日语不规则词，全部为汉字（表意文字）复合词，开发一种日文版的NART （JART）。在100名正常老年人（NE）和70名年龄、性别和教育程度相匹配的阿尔茨海默病（AD）患者的样本中，采用韦氏成人智力量表（WAIS-R）测量了基于JART和IQ的阅读表现。将网元组随机分为网元计算组（n = 50）和网元验证组（n = 50）。利用NE计算组，将观察到的全量表智商（FSIQ）与JART的读数误差进行回归，得到线性回归方程。将网元计算组计算的回归方程应用于网元验证组，预测的FSIQ与观察到的FSIQ充分拟合（R-2 = 0.78）。此外，独立t检验表明，新神经网络组和AD组的jart预测的智商没有显著差异，而AD组在观察到的智商方面表现更差。日本AD患者汉字复合词的阅读能力保存较好。JART是评估AD患者病前智商的有效量表。
The National Adult Reading Test (NART) is widely used as a measure of premorbid IQ of the English-speaking patients with dementia. The purpose of the present study was to develop a Japanese version of the NART (JART), using 50 Japanese irregular words, all of which are Kanji (ideographic script) compound words. Reading performance based on JART and IQ as measured by the Wechsler Adult Intelligence Scale-Revised (WAIS-R) was examined in a sample of 100 normal elderly (NE) persons and in 70 age-, sex-, and education-matched patients with Alzheimer's disease (AD). The NE group was randomly divided into the NE calculation group (n = 50) and the NE validation group (n = 50). Using the NE calculation group, a linear regression equation was obtained in which the observed full-scale IQ (FSIQ) was regressed on the reading errors of the JART. When the regressed equation computed from the NE calculation group was applied to the NE validation group, the predicted FSIQ adequately fit the observed FSIQ (R-2 = 0.78). Further, independent t-tests showed that the JART-predicted IQs were not significantly different between the NE and AD groups, whereas the AD group performed worse in the observed IQs. The reading ability of Kanji compound words is well-preserved in Japanese patients with AD. The JART is a valid scale for evaluating premorbid IQ in patients with AD.