A CLUSTER OF ACINETOBACTER PNEUMONIA IN FOUNDRY WORKERS
A CLUSTER OF ACINETOBACTER PNEUMONIA IN FOUNDRY WORKERS
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DOI：
10.7326/0003-4819-95-6-688
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发表时间：
1981-01-01
影响因子：
39.2
通讯作者：
FRASER, DW
中科院分区：
文献类型：
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作者：
CORDES, LG;BRINK, EW;FRASER, DW
在3个月期间，有3名在铸造厂工作5-19年的钢铸件焊工或研磨工患了由无结核性钙溶弧菌血清型7 j引起的肺炎，其中两人死亡：尸检显示肺部有铁颗粒的混合粉尘尘肺病。从铸造厂空气中分离到7J型无硝酸菌，但未找到来源。铸造厂工人中7J病毒抗体滴度≥64的阳性率（15%）显著高于社区对照组（2%）（P < 0.01）。抽样表明，在铸造厂，焊工和磨工吸入的空气中总颗粒和金属颗粒（特别是铁）以及游离二氧化硅的浓度经常超过可接受的水平。因此，长期接触这些颗粒可能会增加对这种有机体感染的易感性，而这种易感性很少影响健康人。
In a 3 mo. period, 3 men who had worked for 5-19 yr as welders or grinders of steel castings in a foundry acquired pneumonia caused by A. calcoaceticus var. anitratus serotype 7 J. Two of the men died: postmortem examination showed mixed-dust pneumoconiosis with Fe particles in the lungs. A. calcoaceticus var. anitratus serotype 7J was isolated from the air in the foundry but the source was not found. The prevalence of antibody titers of 64 or greater to the 7J strain was significantly higher among foundry workers (15%) than among community controls (2%) (P < 0.01). Sampling showed that the concentrations of total and metallic particles (especially Fe) and of free silica in air inhaled by welders and grinders at the foundry frequently exceeded acceptable levels. Thus, chronic exposure to such particles may increase susceptibility to infection by this organism, which rarely affects healthy people.