Decreased Susceptibility to Azithromycin and Doxycycline in Clinical Isolates of Chlamydia trachomatis Obtained from Recurrently Infected Female Patients in India
Decreased Susceptibility to Azithromycin and Doxycycline in Clinical Isolates of Chlamydia trachomatis Obtained from Recurrently Infected Female Patients in India
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DOI：
10.1159/000314998
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发表时间：
2010-01-01
期刊：
影响因子：
3.3
通讯作者：
Mittal, Aruna
中科院分区：
文献类型：
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作者：
Bhengraj, Apurb Rashmi;Vardhan, Harsh;Mittal, Aruna
背景：生殖道沙眼衣原体反复感染常导致严重的后遗症，对生殖健康有重大影响。材料和方法：复发性感染的症状女性患者进行了测定。采用细胞培养技术对21株临床分离的念珠菌进行了阿奇霉素和强力霉素的体外药敏试验。沙眼阳性患者，包括复发感染的患者。结果：13株（61.9%）分离菌对阿奇霉素和强力霉素敏感，最低抑菌浓度（MIC）为
Background: Recurrent genital Chlamydia trachomatis infection often results in serious sequelae and has a major impact on reproductive health. Materials and Methods: Recurrent infections were determined in symptomatic female patients. In vitro susceptibility assay was performed for azithromycin and doxycycline using the cell culture technique against 21 clinical isolates obtained from C. trachomatis-positive patients including those who were recurrently infected. Results: Thirteen isolates (61.9%) were found to be susceptible to azithromycin and doxycycline with minimum inhibitory concentration (MIC) values