Distribution of vacA and cagA genotypes of Helicobacter pylori in Kuwait
Distribution of vacA and cagA genotypes of Helicobacter pylori in Kuwait
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DOI：
10.1016/j.actatropica.2005.01.004
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发表时间：
2005-03-01
期刊：
影响因子：
2.7
通讯作者：
Junaid, TA
中科院分区：
文献类型：
--
作者：
Al Qabandi, A;Mustafa, AS;Junaid, TA
幽门螺杆菌等位基因类型的分布存在相当大的地理差异。来自科威特的第一项研究确定了胃肠病学中心就诊的 H 7 未经选择的患者中 cagA 和 vacA 基因型的患病率。我们发现，虽然 vacA s1 和 s2 型在中东裔患者的活检中同样可能存在，但非洲阿拉伯人主要感染 s2 型，而南亚人则主要感染 s1 型。南亚人最常携带 cagA 阳性基因型，其中孟加拉国人的患病率最高，为 87%。 (c) 2005 Elsevier B.V. 保留所有权利。
There is considerable geographical variation in the distribution of allelic types of Helicobacter pylori. This first study from Kuwait determined the prevalence of cagA and vacA genotypes among H 7 unselected patients attending a gastroenterology center. We found that whereas vacA s1 and s2 types were equally likely to be present in biopsies obtained from patients of Middle-Eastern origin, African Arabs were predominantly infected with s2 type and South-Asians the s1 type. South Asians most frequently carried the cagA positive genotype with Bangladeshis showing the highest prevalence rate of 87%. (c) 2005 Elsevier B.V. All rights reserved.