Hematocrit is associated with carotid atherosclerosis in men but not in women
Hematocrit is associated with carotid atherosclerosis in men but not in women
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DOI：
10.1097/01.mca.0000071769.74379.49
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发表时间：
2003-06-01
影响因子：
1.8
通讯作者：
Gnasso, A
中科院分区：
文献类型：
--
作者：
Irace, C;Ciamei, M;Gnasso, A
目的验证红细胞压积、全血粘度和血浆粘度是否与颈动脉粥样硬化独立相关，以及它们的测量是否可以改善全球冠心病风险的定义。方法对892名参加心血管疾病预防运动的参与者进行了常规冠心病危险因素(年龄、血压、血脂、血糖、体重指数、腰臀比、吸烟和糖尿病)、红细胞压积、血液和血浆粘度的检测。结果男性年龄、血压、颈动脉内膜中层厚度、红细胞压积(47.4+/-3.7%、47.8+/-3.7%、48.4+/-3.7%，P
Background It is known that blood and plasma viscosities are associated with clinical manifestations of atherosclerosis, though evidence is not conclusive particularly in women.Objective To verify whether hematocrit and blood and plasma viscosities are independently associated with carotid atherosclerosis and whether their measurement can improve the definition of the global coronary heart disease (CHD) risk.Method Eight hundred and ninety-two participants in a cardiovascular disease prevention campaign were examined with regard to conventional CHD risk factors (age, blood pressure, lipids, glucose, body mass index, waist/hip ratio, cigarette smoking and diabetes), hematocrit and blood and plasma viscosities. According to the degree of carotid atherosclerosis, investigated by echo-Doppler, participants were divided in three groups: those without atherosclerosis, those with a low degree of atherosclerosis and those with a high degree of atherosclerosis.Results In men, age, blood pressure, intima-media thickness (IMT), hematocrit (47.4+/-3.7%, 47.8+/-3.7%, 48.4+/-3.7%, P