TREATMENT OF IDIOPATHIC RESPIRATORY-DISTRESS SYNDROME WITH CONTINUOUS POSITIVE AIRWAY PRESSURE
TREATMENT OF IDIOPATHIC RESPIRATORY-DISTRESS SYNDROME WITH CONTINUOUS POSITIVE AIRWAY PRESSURE
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DOI：
10.1056/nejm197106172842401
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发表时间：
1971-01-01
影响因子：
158.5
通讯作者：
HAMILTON, WK
中科院分区：
文献类型：
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作者：
GREGORY, GA;KITTERMAN, JA;HAMILTON, WK
我们对20名患有特发性呼吸窘迫综合征的重症婴儿（出生体重930 ~ 3800 g）进行了持续气道正压通气。他们自发呼吸。通过气管内导管向18名婴儿提供高达12毫米汞柱的压力，并通过婴儿头部周围的压力室向两名婴儿提供压力。动脉氧分压上升，使我们能够在12小时内将吸入的氧气平均降低37.5%。分钟通气量随着持续气道正压通气的增加而减少，但这对动脉二氧化碳分压、pH、动脉血压和肺顺应性的影响很小。16名婴儿存活，其中7名出生时体重低于1500克。
We applied a continuous positive airway pressure to 20 infants (birth weight 930 to 3800 g) severely ill with the idiopathic respiratory-distress syndrome. They breathed spontaneously. Pressure, up to 12 mm of mercury, was delivered through an endotracheal tube to 18 infants and via a pressure chamber around the infant's head to two. Arterial oxygen tension rose in all, permitting us to lower the inspired oxygen an average of 37.5 per cent within 12 hours. Minute ventilation decreased with increased continuous positive airway pressure, but this had little effect on arterial carbon dioxide tension, pH, arterial blood pressure and lung compliance. Sixteen infants survived, including seven of 10 weighing less than 1500 g at birth.