Consistent and precise localization of brain activity in human primary visual cortex by MEG and fMRI
Consistent and precise localization of brain activity in human primary visual cortex by MEG and fMRI
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DOI：
10.1016/s1053-8119(02)00053-8
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发表时间：
2003-03-01
期刊：
影响因子：
5.7
通讯作者：
Ioannides, AA
中科院分区：
文献类型：
--
作者：
Moradi, F;Liu, LC;Ioannides, AA
使用全脑磁图（MEG）和4-T功能性磁共振成像（fMRI）在4名受试者中检查了人类初级视觉皮层（纹状皮层或V1）内活动的断层定位。在视野的下象限，以偏心距为8 °，角位为45 °，以1.8 ° ~ 5.2 °为半径的圆形棋盘格刺激，刺激V1的背侧部，即远离V1/V2界和距状沟底部的部分。功能磁共振成像和脑磁图都确定了每个受试者的目标区域内的空间重叠活动。对于MEG，在3名受试者中，对于两个较大刺激大小（半径4.5和5.2度）中的至少一个，在42 ms时确定了V1的非常精确的激活。当这种V1活动存在时，它标志着在纹状和纹外区的弱兴奋波的开始，该弱兴奋波在50 ms（M50）结束。开始;下一波激活（M70）也以短暂的V1激活为标志，主要在50和60 ms之间。通过fMRI鉴定的V1激活中心和最早的MEG激活之间的平均间隔为3-5 mm。（C）2003 Elsevier Science（USA）。All rights reserved.
The tomographic localization of activity within human primary visual cortex (striate cortex or V1) was examined using whole-head magnetoencephalography (MEG) and 4-T functional magnetic resonance imaging (fMRI) in four subjects. Circular checkerboard pattern stimuli with radii from 1.8 to 5.2degrees were presented at eccentricity of 8 and angular position of 45 in the lower quadrant of the visual field to excite the dorsal part of V1 which is distant from the V1/V2 border and from the fundus of the calcarine sulcus. Both fMRI and MEG identified spatially well-overlapped activity within the targeted area in each subject. For MEG, in three subjects a very precise activation in V1 was identified at 42 ms for at least one of the two larger stimulus sizes (radii 4.5 and 5.2degrees). When this V1 activity was present, it marked the beginning of a weak wave of excitations in striate and extrastriate areas which ended at 50 ms (M50). The beginning of;the next wave of activations (M70) was also marked by a brief V1 activation, mainly between 50 and 60 ms. The mean separation between V1 activation centers identified by fMRI and the earliest MEG activation was 3-5 mm. (C) 2003 Elsevier Science (USA). All rights reserved.