Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: An international consensus
Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: An international consensus
复制标题
DOI：
10.1086/323335
复制
发表时间：
2002-01-01
影响因子：
11.8
通讯作者：
Walsh, TJ
中科院分区：
文献类型：
--
作者：
Ascioglu, S;Rex, JH;Walsh, TJ
在过去的几十年里，免疫功能低下患者的机会性侵袭性真菌感染（IFIs）的频率稳步上升。然而，关于这些ifi的最佳诊断标准存在大量争议。因此，欧洲癌症/侵袭性真菌感染研究和治疗组织合作小组和国家过敏和传染病研究所真菌病研究组的成员组成了一个共识委员会，为临床研究制定ifi的标准定义。在文献综述和国际共识的基础上，对免疫功能低下的癌症患者中最常见和研究的ifi提出了一套以研究为导向的定义。提出了三个层次的概率：“已证明的”、“可能的”和“可能的”。这些定义旨在用于临床和/或流行病学研究，而不是用于临床决策。
During the past several decades, there has been a steady increase in the frequency of opportunistic invasive fungal infections (IFIs) in immunocompromised patients. However, there is substantial controversy concerning optimal diagnostic criteria for these IFIs. Therefore, members of the European Organization for Research and Treatment of Cancer/Invasive Fungal Infections Cooperative Group and the National Institute of Allergy and Infectious Diseases Mycoses Study Group formed a consensus committee to develop standard definitions for IFIs for clinical research. On the basis of a review of literature and an international consensus, a set of research-oriented definitions for the IFIs most often seen and studied in immunocompromised patients with cancer is proposed. Three levels of probability are proposed: "proven," "probable," and "possible." The definitions are intended for use in the context of clinical and/or epidemiological research, not for clinical decision making.