Emotional stimulation processing characteristics in depression: Meta-analysis of eye tracking findings.
Emotional stimulation processing characteristics in depression: Meta-analysis of eye tracking findings.
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DOI：
10.3389/fpsyg.2022.1089654
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发表时间：
2022
影响因子：
3.8
通讯作者：
Chen, Zhencai
中科院分区：
文献类型：
--
作者：
Huang, Genying;Li, Yafang;Zhu, Huizhong;Feng, Hong;Shen, Xunbing;Chen, Zhencai
目的：系统评价抑郁症患者对情绪刺激的注意偏倚，探索区分抑郁患者与健康个体的眼动指标和潜在调节变量。本meta分析纳入了PubMed、Web of Science、ScienceDirect、Cochrane Library、EBSCOhost、Embase、中国知网、万方、VIP等数据库自建库至2022年3月12日发表的关于重度抑郁症眼动追踪的病例对照研究。两位研究者独立筛选文献并进行数据提取。使用纽卡斯尔-渥太华质量评估量表评估文献的质量。采用RevMan 5.4软件进行meta分析。总的来说，纳入了14项研究，包括1167名参与者（非抑郁= 474；非健康= 693）。结果发现：(1)抑郁组对积极情绪刺激的注视时间显著低于健康组；而对于负面刺激，抑郁组的注视时间明显长于健康组。在中性情绪刺激方面，两组间无显著差异。(2)抑郁症患者对正性情绪刺激的注视计数显著低于健康组，而对负性情绪刺激的注视计数显著高于健康组。中性情绪刺激在两组间无显著差异。(3)各组对正性、负性和中性情绪刺激的首次注视时间均无显著差异。(4)亚组分析表明，年龄对积极情绪刺激的注视时间有影响。此外，年龄和负面情绪图片类型（悲伤、不安、威胁、愤怒）影响负面情绪刺激的固着时间。本研究支持抑郁症患者对情绪刺激表现出负向注意偏倚，注视时间和注视次数可作为抑郁症筛查的辅助客观指标。
To systematically evaluate the attentional bias in patients with depression toward emotional stimuli and to explore eye movement indicators and potential regulatory variables that can distinguish such patients from healthy individuals. Case–control studies regarding eye-tracking in major depressive disorder published in PubMed, Web of Science, ScienceDirect, The Cochrane Library, EBSCOhost, Embase, China National Knowledge Infrastructure, Wanfang, and VIP databases from database initiation until March 12, 2022 were included in the present meta-analysis. Two researchers independently screened the literature and performed data extraction. The quality of the literature was assessed using the Newcastle–Ottawa quality assessment scale.RevMan 5.4 software was used for Meta-analysis. Overall, 14 studies were included, including 1,167 participants (Ndepression = 474; Nhealthy = 693). We found that (1) fixation duration was significantly lower for positive emotional stimuli in the depression group than that in the healthy group; however, for negative stimuli, the fixation duration was significantly more in the depression group than in the healthy group. No significant difference was observed in terms of neutral emotional stimuli between groups. (2) Patients with depression exhibited a significantly lower fixation count for positive emotional stimuli than healthy individuals, whereas the fixation count for negative emotional stimuli was significantly higher in the depression group than in the healthy group. No significant difference was found for neutral emotional stimuli between groups. (3) No significant difference was detected in terms of the first fixation duration of the positive, negative, and neutral emotional stimuli between groups. (4) subgroup analysis indicated that age effected fixation duration for positive emotional stimuli. In addition, age and the type of negative emotional picture (sad, dysphoric, threat, anger) effected fixation duration for negative emotional stimuli. Our research supports that patients with depression exhibit a negative attention bias toward emotional stimuli, and the fixation duration and fixation counts may be used as auxiliary objective indicators for depression screening.
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影响因子：
2
作者：
Akram U;Ellis JG;Cau G;Hershaw F;Rajenthran A;Lowe M;Trommelen C;Drabble J
通讯作者：
Drabble J
影响因子：
2.9
作者：
Ao X;Mo L;Wei Z;Yu W;Zhou F;Zhang D
通讯作者：
Zhang D
临床抑郁症的年轻人的选择性注意力的时间过程：一项眼动追踪研究。
影响因子：
4.1
作者：
Kellough, Jennifer L.;Beevers, Christopher G.;Ellis, Alissa J.;Wells, Tony T.
通讯作者：
Wells, Tony T.
影响因子：
2
作者：
Ke, Tianyuan;Wu, Jia;Crowley, Michael J.
通讯作者：
Crowley, Michael J.
影响因子：
4.2
作者：
Grafton, Ben;Southworth, Felicity;MacLeod, Colin
通讯作者：
MacLeod, Colin