Methylthioadenosine (MeSAdo) phosphorylase deficiency in malignancy.
Methylthioadenosine (MeSAdo) phosphorylase deficiency in malignancy.
复制标题
恶性肿瘤中的甲硫腺苷 (MeSAdo) 磷酸化酶缺乏。
DOI:
10.1007/978-1-4684-5637-0_16
复制
发表时间:
1988
影响因子:
--
通讯作者:
Yamanaka,H
中科院分区:
文献类型:
--
作者:
Carson,DA;Nobori,T;Kajander,EO;Carrera,CJ;Kubota,M;Yamanaka,H
The abnormal growth properties of cancer cells must be mediated finally by changes in specific metabolic pathways. In general, malignant transformation is associated with an increase in the activities of enzymes involved in DNA, RNA, and protein synthesis, and a concomitant decrease in the activities of enzymes that degrade cellular metabolites. However, no specific metabolic pathway has been found that distinguishes normal from malignant cells, or is common to all tumors.