Agreement among insulin sensitivity indexes on the diagnosis of insulin resistance in polycystic ovary syndrome and ovulatory women
Agreement among insulin sensitivity indexes on the diagnosis of insulin resistance in polycystic ovary syndrome and ovulatory women
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DOI：
10.1016/j.ejogrb.2006.10.038
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发表时间：
2007-08-01
影响因子：
2.6
通讯作者：
dos Reis, Rosana M.
中科院分区：
文献类型：
--
作者：
de Paula Martins, Wellington;Santana, Laura F.;dos Reis, Rosana M.
目的：比较排卵期妇女和多囊卵巢综合征（PCOS）患者胰岛素敏感性指标对胰岛素抵抗（IR）诊断的一致性。研究设计：在一项观察性研究中，对105名多囊卵巢综合征女性和51名排卵期女性进行75 g口服葡萄糖耐量试验。胰岛素敏感性指标为胰岛素定量敏感性检查指数（QUICKI）、1/稳态模型评估-胰岛素抵抗指数（1/HOMA-IR）、胰岛素曲线下面积（AUC-I）和松田胰岛素敏感性指数（COMP）。对于IR诊断，我们使用了最近出版物中描述的截止值（胰岛素bb0 12 μ IU/ml， 1/HOMA-IR）
Objective: The objective was to compare agreement on the diagnosis of insulin resistance (IR) among insulin sensitivity indexes in both ovulatory women and those with polycystic ovary syndrome (PCOS).Study design: In an observational study, the 75-g oral glucose tolerance test was performed in 105 women with PCOS and 51 ovulatory women. The insulin sensitivity indexes used were insulin quantitative sensitivity check index (QUICKI), 1/homeostasis model assessment-insulin resistance (1/HOMA-IR), area under curve for insulin (AUC-I), and the Matsuda insulin sensitivity index (COMP). For the IR diagnosis we used cut-off values described in recent publications (insulin >12 mu IU/ml, 1/HOMA-IR