A direct physiological trade-off between personal and social immunity
A direct physiological trade-off between personal and social immunity
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DOI：
10.1111/1365-2656.12047
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发表时间：
2013-07-01
影响因子：
4.8
通讯作者：
Kilner, Rebecca M.
中科院分区：
文献类型：
--
作者：
Cotter, Sheena C.;Littlefair, Joanne E.;Kilner, Rebecca M.
最近的研究表明，生物体具有两种免疫反应策略：保护个人的个人免疫和保护其他个人(如亲属)的社会免疫。然而，目前尚不清楚个人如何在保护自己和保护他人之间分配有限的资源。在这里，通过对雌性埋葬甲虫的实验，我们挑战了个人免疫系统，并测量了随后在社会免疫方面的投入(肛门分泌物的抗菌活性)。我们的结果表明，在个人免疫的一个方面(伤口修复)增加投资，会导致社会免疫反应的一个方面暂时下降。我们的实验进一步表明，通过在一次繁殖尝试中以这种方式平衡对个人和社会免疫的投资，雌性能够捍卫自己随后的终生繁殖成功。我们讨论了在优势性和殖民性程度不同的物种中个人免疫和社会免疫之间的生理权衡的性质，并建议它也可能在物种内因年龄和伴侣对社会免疫的贡献而不同。
Recent work shows that organisms possess two strategies of immune response: personal immunity, which defends an individual, and social immunity, which protects other individuals, such as kin. However, it is unclear how individuals divide their limited resources between protecting themselves and protecting others. Here, with experiments on female burying beetles, we challenged the personal immune system and measured subsequent investment in social immunity (antibacterial activity of the anal exudates). Our results show that increased investment in one aspect of personal immunity (wound repair) causes a temporary decrease in one aspect of the social immune response. Our experiments further show that by balancing investment in personal and social immunity in this way during one breeding attempt, females are able to defend their subsequent lifetime reproductive success. We discuss the nature of the physiological trade-off between personal and social immunity in species that differ in the degree of eusociality and coloniality, and suggest that it may also vary within species in relation to age and partner contributions to social immunity.