Primary sensorimotor cortex activation with task-performance after fatiguing hand exercise
Primary sensorimotor cortex activation with task-performance after fatiguing hand exercise
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DOI：
10.1007/s00221-005-0013-2
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发表时间：
2005-11-01
影响因子：
2
通讯作者：
Thickbroom, GW
中科院分区：
文献类型：
--
作者：
Benwell, NM;Byrnes, ML;Thickbroom, GW
我们比较了功能性MRI信号在初级感觉运动皮层（SM 1）在每只手的起搏运动任务之前和之后unimanual（右手）疲劳运动。我们的目的是确定激活的程度是否是不同的，当一个运动任务进行疲劳运动后，以及是否有任何差异，在激活之间的运动疲劳和非疲劳的手。在疲劳手（运动前38 +/- 5 vs运动后21 +/- 3; P < 0.05）和非疲劳手（运动前32 +/- 4 vs运动后18 +/- 4; P < 0.05）运动的对侧半球，SM 1中激活的体素数量显著减少。运动前后功能性磁共振成像信号的幅度没有显著差异，然而，运动后方差显著增加（运动前6.0 +/- 0.5 vs运动后7.3 +/- 0.6; P < 0.01）。SM 1的功能激活减少可能反映了激活的可变性增加，而不是疲劳后皮质运动网络激活的减少。
We have compared functional MRI signals in primary sensorimotor cortex (SM1) during a paced motor task of each hand before and after unimanual (right hand) fatiguing exercise. Our aims were to determine whether the degree of activation is different when a motor task is performed after a fatiguing exercise, and whether there are any differences in activation between movement of the fatigued and non-fatigued hands. There was a significant reduction in the number of voxels activated in SM1 in the hemisphere contralateral to movement of both the fatigued hand (38 +/- 5 pre-exercise versus 21 +/- 3 post-exercise; P < 0.05) and the non-fatigued hand (32 +/- 4 pre-exercise vs 18 +/- 4 post-exercise; P < 0.05). There was no significant difference in the magnitude of the functional magnetic resonance imaging signal before or after exercise, however, the variance increased significantly after exercise (6.0 +/- 0.5 pre-exercise vs 7.3 +/- 0.6 post-exercise; P < 0.01). Reduced functional activation in SM1 may reflect increased variability in the activation rather than a reduction in activation of cortical motor networks after fatigue.