PROJECTIONS OF THE AMYGDALA TO THE THALAMUS IN THE CYNOMOLGUS MONKEY
PROJECTIONS OF THE AMYGDALA TO THE THALAMUS IN THE CYNOMOLGUS MONKEY
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DOI：
10.1002/cne.902220106
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发表时间：
1984-01-01
影响因子：
2.5
通讯作者：
MISHKIN, M
中科院分区：
文献类型：
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作者：
AGGLETON, JP;MISHKIN, M
采用顺行和逆行轴突追踪技术研究了食蟹猴（M. fasciculis）杏仁核到丘脑的投射。将辣根过氧化物酶 (HRP) 注射到 5 只动物的内侧和中线丘脑部位，并将 [3H] 氨基酸注射到 10 只动物总共 13 个半球的选定杏仁区域。两种类型的示踪剂实验证明了杏仁核投射到两个丘脑背内侧核（MD）和团聚核的起源、过程和终端模式。几乎所有的杏仁核都对 MD 做出贡献，尽管最大比例来自基底组，并终止于 MD 内侧大细胞部分内的离散、互锁斑块。除了这个主要投射之外，中央和内侧杏仁核还向团聚核的外侧部分发送较轻的投射。杏仁丘脑投射通过多种路线离开杏仁核，然后大多数加入丘脑下脚并进入丘脑头端，在那里它们尾部转向目标。少量杏仁丘脑纤维也可能在终纹中运行。
The projections of the amygdala to the thalamus in cynomolgus monkeys (M. fascicularis) were studied with both anterograde and retrograde axonal tracing techniques. Horseradish peroxidase (HRP) was injected into medial and midline thalamic sites in 5 animals, and [3H] amino acids were injected into selected amygdaloid regions in a total of 13 hemispheres in 10 animals. The 2 types of tracer experiments demonstrated the origins, course and terminal pattern of amygdaloid projections to 2 thalamic nuclei-medialis dorsalis (MD) and reuniens. Almost all of the amygdaloid nuclei contribute projections to MD, though the greatest proportion arise from the basal group and terminate in discrete, interlocking patches within the medial, magnocellular portion of MD. In addition to this major projection, the central and medial amygdaloid nuclei send a lighter projection to the lateral portion of nucleus reuniens. The amygdalothalamic projections took a variety of routes out of the amygdala before the large majority joined the inferior thalamic peduncle and entered the rostral head of the thalamus where they turned caudally toward their targets. A small number of amygdalothalamic fibers may also run in the stria terminalis.