Symptoms of depression and changes in body weight from adolescence to mid-life
Symptoms of depression and changes in body weight from adolescence to mid-life
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DOI：
10.1038/sj.ijo.0800647
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发表时间：
1998-07-01
影响因子：
4.9
通讯作者：
Siegler, IC
中科院分区：
文献类型：
--
作者：
Barefoot, JC;Heitmann, BL;Siegler, IC
目的：通过 20 多年的随访，调查体重正常的健康个体抑郁症状与体重变化的关系。 参与者和设计：在 20 世纪 60 年代中期，对大学生（3885 名男性和 841 名女性）进行了自我报告抑郁症测量。他们的基线体重指数（BMI）是根据他们的大学病历计算得出的。 20 世纪 80 年代末，我们通过邮件联系参与者，要求他们报告目前的身高和体重以及吸烟和锻炼习惯。另一项抑郁症状的测量是从 3560 名受试者的随访中获得的。使用多元回归模型将体重变化与抑郁评分联系起来，同时控制背景（性别、基线 BMI 和 BMI 相互作用的性别）和行为（运动和吸烟）预测因素。 结果：抑郁症状和体重变化之间的关系采取与基线 BMI 相互作用的形式（P < 0.001）。那些基线抑郁评分高的人，如果他们最初很瘦，那么他们的体重就会比没有抑郁的人增加得更少，但如果他们最初很重，那么他们的体重就会增加更多。这种趋势在基线和随访时抑郁评分较高的人群中尤其明显。结论：研究结果支持抑郁症夸大了先前存在的体重变化趋势的假设。仅通过检查主效应是无法检测到这种模式的，这说明在心理因素和体重的研究中需要转向更复杂的交互模型。
OBJECTIVE: To investigate the relationship of symptoms of depression to weight changes in healthy individuals of normal weight across a follow-up of over 20 y.PARTICIPANTS AND DESIGN: College students (3885 men and 841 women) were administered a self-report depression measure in the mid-1960s. Their baseline body mass index (BMI) was calculated from their college medical records. Participants were contacted by mail in the late 1980s and asked to report their current height and weight as well as their smoking and exercise habits. Another measure of depressive symptoms was obtained from 3560 individuals at follow-up. Multiple regression models were used to relate changes in weight to depression scores while controlling for background (gender, baseline BMI and the gender by BMI interaction) and behavioral (exercise and smoking) predictors.RESULTS: The relationship between depressive symptoms and body weight change took the form of an interaction with baseline BMI (P < 0.001). Those with high baseline depression scores gained less weight than their nondepressed counterparts if they were initially lean, but more if they were initially heavy. This trend was especially strong in those with high depression scores at both baseline and follow-up.CONCLUSIONS: The findings support the hypothesis that depression exaggerates pre-existing weight change tendencies. This pattern would not have been detected by an examination of main effects alone, illustrating the need to move toward more complicated interactive models in the study of psychological factors and weight.