Rod, M-cone and M/S-cone inputs to hyperpolarizing bipolar cells in the mouse retina.
Rod, M-cone and M/S-cone inputs to hyperpolarizing bipolar cells in the mouse retina.
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杆、M-锥体和 M/S-锥体输入到小鼠视网膜中的超极化双极细胞。
DOI：
10.1113/jphysiol.2011.224113
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Wu,SamuelM
中科院分区：
文献类型：
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作者：
Pang,Ji-Jie;Gao,Fan;Paul,DavidL;Wu,SamuelM
ON和OFF通路是视觉系统的主要信息处理通道，并且它们开始于视网膜双极细胞水平。在这里，我们展示了一个系统的研究相关的光响应特性和细胞形态的OFF（超极化）双极细胞（HBCs）在小鼠视网膜。这项研究的结果描述了视杆细胞、M-视锥细胞和M/S-视锥细胞如何介导三种主要类型的HBC的反应，以及OFF通路中的突触如何相互连接以服务于各种视觉任务。
Non‐technical summaryON and OFF pathways are major information processing channels of the visual system, and they begin at the retinal bipolar cell level. Here we show a systematic study correlating light response characteristics and cell morphology of OFF (hyperpolarizing) bipolar cells (HBCs) in the mouse retina. Results from this study provide a description of how rods, M‐cones and M/S‐cones mediate responses in three major types of HBCs, and how synapses in the OFF pathway are interconnected to serve various visual tasks.