1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (platelet-activating factor) stimulates calcium influx in rabbit platelets.
1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (platelet-activating factor) stimulates calcium influx in rabbit platelets.
复制标题
1-烷基-2-乙酰基-sn-甘油-3-磷酸胆碱（血小板激活因子）刺激兔血小板中的钙流入。
DOI：
10.1016/s0006-291x(81)80147-7
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发表时间：
1981
影响因子：
3.1
通讯作者：
Snyder,F
中科院分区：
文献类型：
--
作者：
Lee,TC;Malone,B;Blank,ML;Snyder,F
1-烷基-2-乙酰基-sn-甘油-3-磷酸胆碱（血小板活化因子）诱导兔血小板内Ca 2+内流，其具有时间、温度和浓度依赖性。1-烷基-2-乙酰基-sn-甘油-3-磷酸胆碱的离子电泳活性比3-十六烷基-2-乙酰基-sn-甘油-1-磷酸胆碱、1-十六烷基-2-溶血-sn-甘油-3-磷酸胆碱、1-酰基-2-乙酰基-sn-甘油-3-磷酸胆碱或1-十六酰基-2-溶血-sn-甘油-3-磷酸胆碱高得多（在10− 10 M时>2倍）。
1-Alkyl-2-acetyl-sn-glycero-3-phosphocholine (platelet-activating factor) induces an influx of Ca2+in rabbit platelets that is time-, temperature-, and concentration-dependent. The ionophoretic activity of 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine is much higher (>2-fold at 10−10M) than 3-hexadecyl-2-acetyl-sn-glycero-l-phosphocholine, 1-hexadecyl-2-lyso-sn-glycero-3-phosphocholine, 1-acyl-2-acetyl-sn-glycero-3-phosphocholine, or 1-hexadecanoyl-2-lyso-sn-glycero-3-phosphocholine.