Burden of tuberculosis and its association with socio-economic development status in 204 countries and territories, 1990-2019.
Burden of tuberculosis and its association with socio-economic development status in 204 countries and territories, 1990-2019.
复制标题
DOI：
10.3389/fmed.2022.905245
复制
发表时间：
2022
影响因子：
3.9
通讯作者：
Jia CY
中科院分区：
文献类型：
--
作者：
Xue Y;Zhou J;Wang P;Lan JH;Lian WQ;Fan YY;Xu BN;Yin JP;Feng ZH;Zhou J;Jia CY
在传染病方面，结核病（TB）始终是全球负担的首要问题。结核病可导致生活质量下降、经济困难、歧视、边缘化和社会障碍，是一个重大的公共卫生问题。结核病负担和趋势评估可以为决策和规划提供重要信息，帮助世界各国实现2030年结束结核病流行的可持续发展目标。所有数据均来自2019年全球疾病负担（GBD 2019）数据库，该数据库分析了过去30年来结核病和艾滋病毒/艾滋病感染结核病的年龄标准化发病率、死亡率和死亡率的负担趋势。此外，GBD 2019不仅分析了全球204个国家和主要地区的结核病负担分布，还分析了全球结核病负担与社会人口指数（SDI）之间的关系。艾滋病毒阴性结核病的年龄标准化发病率、年龄标准化残疾调整生命年（DIMs）和年龄标准化死亡率为10，671.45（9，395.60 - 12，194.10）、59，042.45（53，684.78 - 64，641.53）和1，463.62（1，339.24 - 1，602.71）（95%CI，每10万人-年）。HIV/AIDS-XDR-TB的标准化发病率、年龄标准化死亡率和年龄标准化死亡率（95%CI，每1,000人-年）分别为2.10（1.51-2.90）、64.23（28.64-117.74）和1.01（0.42-1.86）。我们发现结核病与SDI、年龄标准化发病率、DALYs和死亡率成反比，低负担国家位于高SDI地区，而高负担国家位于低SDI地区。全球结核病呈缓慢下降趋势，但HIV阳性结核病年龄标化发病率呈上升趋势，且主要分布在撒哈拉以南非洲地区。结核病的标化发病率、年龄标化死亡率和年龄标化死亡率与SDI有关，低SDI国家的负担轻于高SDI国家。如果不采取有效措施，世界各国将难以实现到2030年结束结核病流行的目标。有效控制结核病的传播需要世界各国的共同努力，特别是低SDI国家，需要改进结核病的诊断和预防措施，提高HIV/AIDS-TB的控制水平。
Tuberculosis (TB) always runs in the forefront of the global burden when it comes to infectious diseases. Tuberculosis, which can lead to impairment of quality of life, financial hardship, discrimination, marginalization, and social barriers, is a major public health problem. The assessment of TB burden and trend can provide crucial information for policy decision and planning, and help countries in the world to achieve the goal of sustainable development of ending the epidemic of TB in 2030. All data are from the Global Burden of Disease 2019 (GBD 2019) database, which analyzed the burden trend of age-standardized incidence, DALYs, and deaths rate in TB and HIV/AIDS-infected TB over the past 30 years. Also, GBD 2019 not only analyzed the burden distribution of TB in 204 countries and main regions of the world but also analyzed the relationship between the burden of global TB and the socio–demographic Index (SDI). The age-standardized incidence, age-standardized disability-adjusted life years (DALYs), and age-standardized deaths rate for HIV-negative TB were 10,671.45 (9,395.60–12,194.10), 59,042.45 (53,684.78–64,641.53), and 1,463.62 (1,339.24–1,602.71) (95% CI, per 100,000 person-years) in 2019, respectively. Age-standardized incidence, age-standardized DALYs, and age-standardized deaths rate of HIV/AIDS-XDR-TB (95% CI, per 1,000 person-years) were 2.10 (1.51–2.90), 64.23 (28.64–117.74), and 1.01 (0.42–1.86), respectively. We found that TB is inversely proportional to SDI, the age-standardized incidence, DALYs, and deaths rate low burden countries were in high SDI areas, while high burden countries were in low SDI areas. The global TB showed a slow decline trend, but the age-standardized incidence of HIV-positive TB was increasing, and mainly distributed in sub-Saharan Africa. Age-standardized incidence, age-standardized DALYs, and age-standardized deaths rate of TB is related to SDI, and the burden of low SDI countries is lighter than that of high SDI countries. Without effective measures, it will be difficult for countries around the world to achieve the goal of ending the TB epidemic by 2030. Effective control of the spread of TB requires concerted efforts from all countries in the world, especially in the countries with low SDI, which need to improve the diagnosis and preventive measures of TB and improve the control of HIV/AIDS-TB.
登录
查看更多内容
影响因子：
3.3
作者：
Murray CJ;Ezzati M;Lopez AD;Rodgers A;Vander Hoorn S
通讯作者：
Vander Hoorn S
影响因子：
168.9
作者：
Micah, Angela E.;Su, Yanfang;Dieleman, Joseph L.
通讯作者：
Dieleman, Joseph L.
影响因子：
168.9
作者：
Murray, CJL;Lopez, AD
通讯作者：
Lopez, AD
DOI：
10.1016/s0140-6736(17)32152-9
发表时间：
2017-09-16
期刊：
Lancet (London, England)
影响因子：
--
作者：
GBD 2016 Causes of Death Collaborators
通讯作者：
GBD 2016 Causes of Death Collaborators
DOI：
10.1016/s0140-6736(17)32130-x
发表时间：
2017-09-16
期刊：
Lancet (London, England)
影响因子：
--
作者：
GBD 2016 DALYs and HALE Collaborators
通讯作者：
GBD 2016 DALYs and HALE Collaborators