Human immunodeficiency virus seroprevalence in community-based primary care practices, 1990-1992. A report from the Ambulatory Sentinel Practice Network.
Human immunodeficiency virus seroprevalence in community-based primary care practices, 1990-1992. A report from the Ambulatory Sentinel Practice Network.
复制标题
DOI：
10.1001/archfami.4.12.1042
复制
发表时间：
1995-12-01
期刊：
影响因子：
--
通讯作者：
Main, D S
中科院分区：
文献类型：
--
作者：
Miller, R S;Green, L A;Main, D S
目的：估计人类免疫缺陷病毒1型（HIV-1）感染的血清阳性率在初级保健practice.METHODS：五十四个做法在美国参加了一个匿名的，无关联的HIV血清阳性率研究1990年1月至1992年12月。从15至49岁患者中采集用于常规临床检测的剩余血样，每季度集中检测1个月的HIV-1抗体。有关患者的人口统计学信息，临床医生公认的危险因素，已知的艾滋病病毒感染状况的患者，以及是否抽取血液进行艾滋病病毒检测记录与每个samples.Results：收集的21,998标本，99（0.45%）血清阳性。在这99名血清阳性者中，31.3%（血清阳性率为0.15%）的人没有被他们的临床医生怀疑感染了艾滋病毒。男子的血清阳性率（0.96%）高于妇女（0.22%），农村地区（0.18%）低于城市地区（0.71%）。然而，在未被怀疑感染艾滋病毒的患者中，性别差异不太明显，特别是在农村地区。艾滋病毒感染的危险因素很少被注意到。在1990年至1992年的研究期间（0.36%至0.53%）的总体血清阳性率有增加，但是，这种趋势是没有统计学意义的。结论：在3年的时间内，临床医生在至少两个五个初级保健的做法可以预期遇到感染艾滋病毒的患者，无论实践的位置。此外，近三分之一的艾滋病毒感染者不会被他们的临床医生怀疑有这种情况。
OBJECTIVE: To estimate the seroprevalence of human immunodeficiency virus type 1 (HIV-1) infection in primary care practices.METHODS: Fifty-four practices in the United States participated in an anonymous, unlinked HIV seroprevalence study between January 1990 and December 1992. Residual blood samples drawn for routine clinical tests from patients 15 to 49 years of age were centrally tested for the HIV-1 antibody for 1 month of each quarter. Information about patient demographics, clinician-recognized risk factors, the known HIV status of the patient, and whether the blood was drawn for HIV testing was recorded with each specimen.RESULTS: Of 21,998 specimens collected, 99 (0.45%) were seropositive. Of these 99 seropositive persons, 31.3% (a seroprevalence of 0.15%) were not suspected by their clinicians of being infected with HIV. Seroprevalences in men (0.96%) exceeded those in women (0.22%), and rates in rural practices (0.18%) were lower than in urban practices (0.71%). Among patients with unsuspected HIV infection, however, the gender differences, especially in rural areas, were less pronounced. Risk factors for HIV infection were infrequently noted. There was an increase in the overall seroprevalence during the 1990 to 1992 study period (0.36% to 0.53%); however, this trend was not statistically significant.CONCLUSIONS: Within a 3-year period, clinicians in at least two of five primary care practices can expect to encounter patients infected with HIV, regardless of practice location. Also, nearly one third of the patients with HIV infection will not be suspected of having this condition by their clinician.