The Aliphatic Alcohols
The Aliphatic Alcohols
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脂肪醇
DOI：
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发表时间：
1984
期刊：
影响因子：
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通讯作者：
A. M. Potts
中科院分区：
文献类型：
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作者：
A. M. Potts
What may be called the “organic solvent properties” of the aliphatic alcohols manifest themselves in higher animals in narcosis and, eventually, death. These properties become more manifest with increasing length of the aliphatic chain (von Oettingen 1943; Mardones 1963). In this series ethanol has a special place. Its relatively high ratio of lethal to pharmacologic dose has led to its use and abuse throughout recorded history (cf. Gen. 9.20–21). Only with ethanol has reliable investigation been done on human subjects. Extensive studies of sublethal dose effects have been recorded. It has become clear that the organic solvent properties which ethanol shares with the other aliphatic alcohols and many other small organic molecules is the ability to act selectively on the central nervous system.
