Microdosimetry on a Mini-Reactor UTR-KINKI for Educational Uses and Biological Researches
Microdosimetry on a Mini-Reactor UTR-KINKI for Educational Uses and Biological Researches
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DOI：
10.1269/jrr.08072
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发表时间：
2009-01-01
影响因子：
2
通讯作者：
Shizuma, Kiyoshi
中科院分区：
文献类型：
--
作者：
Endo, Satoru;Tanaka, Kenichi;Shizuma, Kiyoshi
在近畿大学的教育和研究小型反应堆（UTR-KINKI）中，使用组织等效气体正比计数器（TEPC）进行了微剂量学研究。微剂量单事件谱为0.5，1，2，3和5 μ m的网站大小获得的线性能量范围从1到1000 keV/μ m。中子和γ射线的分数剂量估计从单事件谱。的中子剂量分数从35%到55%的0.5至5 μ m的网站大小。同样估计了每个位点大小的平均线性能量y（D），发现其取决于位点大小。中子的平均线能量略大于来自（252）Cf的裂变中子的平均线能量，而γ射线的平均线能量与25 keV γ射线和250 W X射线具有相似的位置尺寸依赖性。使用Tilikidis的2 Gy响应函数，发现UTR-KINKI的相对生物学有效性为4.1 +/- 0.13。UTR-KINKI中子的RBE估计值非常接近先前青鳉鳃细胞微核细胞的生物学实验值4.3 +/- 0.6和ICR小鼠胸腺淋巴细胞凋亡诱导的生物学实验值4.6 +/- 0.5。
Microdosimetry study has been carried out at the education and research mini-reactor of Kinki University (UTR-KINKI) using a tissue equivalent gas proportional counter (TEPC). The microdosimetric single event spectra for 0.5, 1, 2, 3 and 5 mu m site sizes were obtained in the lineal energy range from I to 1000 keV/mu m. Neutron and gamma-ray fractional doses were estimated from the single event spectra. The neutron dose fraction was varied from 35 to 55% for 0.5 to 5 mu m site size. The averaged lineal energy, y(D), for each site size was likewise estimated and found to be dependent on the site size. The averaged lineal energy for neutron was slightly larger than that of the fission neutrons from (252)Cf, and the averaged lineal energy for gamma-ray had similar site-size-dependence of 25 keV gamma-rays and 250 W X-rays. Relative biological effectiveness was found to be 4.1 +/- 0.13 for UTR-KINKI using Tilikidis's 2 Gy-response function. The estimated RBE for UTR-KINKI neutrons is quite close to the previous biological experimental value of 4.3 +/- 0.6 for micronucleated cells in gill cell of Medaka and 4.6 +/- 0.5 for induction of lymphocyte apoptosis in the thymus of ICR mice.