Shrinkage as a potential mechanism of recurrent clinical events in patients with a large vulnerable plaque
Shrinkage as a potential mechanism of recurrent clinical events in patients with a large vulnerable plaque
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收缩是具有大的易损斑块的患者复发临床事件的潜在机制
DOI：
10.2459/jcm.0000000000000783
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发表时间：
2019-08-01
影响因子：
3
通讯作者：
Yu, Bo
中科院分区：
文献类型：
--
作者：
Liu, Xianglan;Sun, Changbin;Yu, Bo
目的：本研究旨在通过光学相干断层扫描（OCT）和血管内超声（IVUS）研究冠状动脉疾病患者中斑块负荷至少为70%的易损斑块病变的进展和血管收缩。方法47例患者的五十六例OCT确定的易损斑块包括在冠状动脉造影确定的非罪犯/非靶病变中。结果35个小易损斑块（斑块负荷= 70%，B组）被确定。基线时IVUS结果显示平均斑块面积（P
Aims This study aimed to investigate the progression and vascular shrinkage of vulnerable plaque lesions with a plaque burden at least 70% among patients with coronary artery disease by optical coherence tomography (OCT) and intravascular ultrasound (IVUS).Methods Fifty-six OCT-identified vulnerable plaques from 47 patients were included among coronary angiography-identified nonculprit/nontarget lesions. Serial IVUS images were used to assess plaque progression and vascular shrinkage.Results Thirty-five small vulnerable plaques (plaque burden = 70%, group B) were identified. The IVUS results at baseline show that mean plaque areas (P