The Poole Diabetes Study: how many cases of Type 2 diabetes are diagnosed each year during normal health care in a defined community?
The Poole Diabetes Study: how many cases of Type 2 diabetes are diagnosed each year during normal health care in a defined community?
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DOI：
10.1016/s0168-8227(01)00245-5
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发表时间：
2001-08-01
影响因子：
5.1
通讯作者：
Mullee, MA
中科院分区：
文献类型：
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作者：
Gatling, W;Guzder, RN;Mullee, MA
我们调查了普尔地区新诊断的2型糖尿病的发病率，并将其外推到英国其他地区。方法：这项前瞻性观察性研究采用了初级和二级保健的监测方案。我们确定了1996年5月至1998年6月30日期间，在普尔地区24个初级保健诊所登记的186889人中，通过正常的卫生保健程序，未进行主动筛查，新诊断的2型糖尿病的所有病例。结果：1996年该人群2型糖尿病患病率为1.59（95%CI 1.53-1.65%）%。在研究的前24个月，确定了706例新的2型糖尿病病例，其中383例男性和324例女性。因此，新诊断的2型糖尿病的粗年发病率为1.93/1000（95% CI 1.73-2.13%），年龄/性别校正的发病率为1.67/1000（95% CI 1.49-1.84%）。男性的年龄校正发生率为1.86/1000（95%CI 1.60-2.13），高于女性的1.48/1000（95%CI 1.25-1.71%），相对风险为1.26（95%CI 0.997-1.527%），但该差异未达到统计学显著性。诊断时平均HbA（1c）为10.8（S.D.）。2.9%）。男性在诊断时比女性年轻（平均年龄，62.9 vs. 65.9%，P
We have investigated the incidence of newly diagnosed Type 2 diabetes in the Poole area and extrapolated it to the rest of the UK. Methods: this prospective observational study used a surveillance programme in primary and secondary care. We identified all cases of newly diagnosed Type 2 diabetes mellitus occurring from ist May 1996 to 30th June 1998 through the normal health care process without ally active screening in 186889 people registered with 24 primary care practices in the Poole area. Results: the 1996 prevalence of diagnosed Type 2 diabetes in this population was 1.59 (95% CI 1.53-1.65%)%. During the first 24 months of the study, 706 new cases of Type 2 diabetes mellitus, 383 men and 324 women, were identified. The crude annual incidence of newly diagnosed Type 2 diabetes, thus was 1.93/1000 (95% CI 1.73-2.13%) and age/sex adjusted incidence was 1.67/1000 (95% CI 1.49-1.84%). The age-adjusted incidence was higher in men, 1.86/1000 (95% CI 1.60-2.13), than in women, 1.48/1000 (95% CI 1.25-1.71%), relative risk 1.26 (95% CI 0.997-1.527%), but this difference did not reach statistical significance. Mean HbA(1c) at diagnosis was 10.8 (S.D. 2.9%)%. Men were younger at diagnosis than women (mean age, 62.9 vs. 65.9%, P