Reemergence of Chikungunya Virus
Reemergence of Chikungunya Virus
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DOI：
10.1128/jvi.01432-14
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发表时间：
2014-10-01
影响因子：
5.4
通讯作者：
Morrison, Thomas E.
中科院分区：
文献类型：
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作者：
Morrison, Thomas E.
基孔肯雅病毒（CHIKV）是一种蚊子传播的甲病毒，可引起人类急性发热以及急性和慢性肌肉骨骼疼痛。自2004年以来，CHIKV已在印度洋地区造成数百万病例，并在欧洲、中东和太平洋地区等新地区出现。这种病毒的蚊子媒介在全球分布在热带和温带，这为CHIKV继续扩展到新的地理区域提供了机会。2013年10月，在加勒比海圣马丁岛发现了当地获得的CHIKV感染病例，标志着该病毒抵达西半球。在短短9个月内，CHIKV已经传播到加勒比海和中南美洲的22个国家，导致数十万例病例。CHIKV疾病可以高度使人衰弱，并且大规模流行具有严重的经济后果。因此，迫切需要继续研究这些感染的流行病学、发病机制、预防和治疗。
Chikungunya virus (CHIKV) is a mosquito-transmitted alphavirus that causes acute fever and acute and chronic musculoskeletal pain in humans. Since 2004, CHIKV has caused millions of cases of disease in the Indian Ocean region and has emerged in new areas, including Europe, the Middle East, and the Pacific region. The mosquito vectors for this virus are globally distributed in tropical and temperate zones, providing the opportunity for CHIKV to continue to expand into new geographic regions. In October 2013, locally acquired cases of CHIKV infection were identified on the Caribbean island of Saint Martin, signaling the arrival of the virus in the Western Hemisphere. In just 9 months, CHIKV has spread to 22 countries in the Caribbean and Central and South America, resulting in hundreds of thousands of cases. CHIKV disease can be highly debilitating, and large epidemics have severe economic consequences. Thus, there is an urgent need for continued research into the epidemiology, pathogenesis, prevention, and treatment of these infections.